摘要：
In recent years, carbon-based materials catalyzing peroxymonosulfate (PMS) for green degradation of persistent or-ganic pollutants have attracted increasing attention. However, PMS activation by hydrochar composite (e.g. hydrochar-montomorillonite) has rarely been investigated. Herein, a simple preparation, low-cost and eco-friendly catalyst of hydrochar-montmorillonite composite (HC-Mt) was prepared to firstly catalyze PMS for the degradation of dicamba (DIC). The as-prepared HC-Mt showed a remarkably better catalyzing performance for PMS than pure hydrochar (HC) due to its good physicochemical characteristics and abundant oxygen-containing groups. Further-more, the electron spin resonance (ESR) and quenching tests revealed that active species such as SO4 center dot-, center dot OH and O2 center dot- all participated in the degradation process. DIC sites on C6, Cl 10, and O15 exhibited higher reactivity according to the density functional theory (DFT) calculation, which were easily attacked by active species. The DIC degradation mainly occurred via hydroxyl substitution, decarboxylation, oxidation and ring-cleavage and finally most of the inter-mediates were mineralized into CO2 and H2O. Finally, the phytotoxicity assessment was measured by the germination growth situation of tobacco and mung beans in the presence of DIC (with or without treatment by HC-Mt/PMS). The result showed that HC-Mt/PMS could significantly reduce the phytotoxicity of DIC to crops, suggesting that catalyzing PMS using HC-Mt was environmentally friendly. Therefore, this work did not only provide a novel catalyzing PMS strategy using hydrochar composite for wastewater treatment, but also give a new idea for herbicide phytotoxicity management.
期刊：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2023年300:122951 ISSN：1386-1425
通讯作者：
Gu, B
作者机构：
[Zhang, Keyang; Dai, Cong; Gu, Biao; Tang, Can; Zhao, Jingjun; Li, Xinyu; Gu, B] Hengyang Normal Univ, Coll Chem & Mat Sci, Hunan Prov Engn Res Ctr Monitoring & Treatment Hea, Key Lab Organomet New Mat, Hengyang 421008, Peoples R China.
通讯机构：
[Gu, B ] H;Hengyang Normal Univ, Coll Chem & Mat Sci, Hunan Prov Engn Res Ctr Monitoring & Treatment Hea, Key Lab Organomet New Mat, Hengyang 421008, Peoples R China.
关键词：
AIE;Bioimaging;Continuous detection;Cu(2+) and H(2)S;Fluorescent sensor
摘要：
The development of effective methods for tracking Cu(2+) and H(2)S in living organisms is urgently required due to their vital function in a variety of pathophysiological processes. In this work, a new fluorescent sensor BDF with excited-state intramolecular proton transfer (ESIPT) and aggregation-induced emission (AIE) features for the successive detection of Cu(2+) and H(2)S was constructed by introducing 3,5-bis(trifluoromethyl)phenylacetonitrile into the benzothiazole skeleton. BDF showed a fast, selective and sensitive fluorescence "turn off" response to Cu(2+) in physiological media, and the situ-formed complex can serve as a fluorescence "turn on" sensor for highly selective detection of H(2)S through the Cu(2+) displacement approach. In addition, the detection limits of BDF for Cu(2+) and H(2)S were determined to be 0.05 and 1.95μM, respectively. Encouraged by its favourable features, including strong red fluorescence from the AIE effect, large Stokes shift (285nm), high anti-interference ability and good function at physiological pH as well as a low toxicity, BDF was successfully applied for the consequent imaging of Cu(2+) and H(2)S in both living cells and zebrafish, making it an ideal candidate for detecting and imaging of Cu(2+) and H(2)S in live systems.
摘要：
Mercury ions (Hg(2+)), as one of heavy transition metals (HTM), is a highly toxic metal that is hazardous to human health. Here an aggregation-induced emission (AIE) fluorescent probe is designed for the highly sensitive and selective detection of Hg(2+). The probe is engineered with a tetraphenylethene (TPE) derivative as the fluorophore and thiopropionic acid as the site of recognition for Hg(2+). Due to the different solubilities of the probe AIE-COOH and its corresponding product after reaction with Hg(2+). The probe demonstrates a maximum detection limit of 22nM and a fast response time of∼100s. Simultaneously, AIE-COOH exhibits outstanding detectivity and hypersensitivity for the detection of Hg(2+) in aqueous solutions. These characteristics demonstrate that AIE-COOH hold a great potential in environmental, food and biological systems. Moreover, we have also successfully applied it to Hg(2+) fluorescence imaging in in living cells.
摘要：
The abnormal accumulation of copper ions (Cu(2+)) is considered to be one of the pathological factors of Alzheimer's disease (AD), but the internal relationship between Cu(2+) and AD progression is still not fully clear. In this work, a sensitive and selective near-infrared fluorescent copper ion probe (DDP-Cu) was designed for quantification and visualization of Cu(2+) level in lysates, living cells, living zebrafish and brain tissues of drosophila and mice with AD. By using this probe, we demonstrated that the content of Cu(2+) in the brains of AD mice and drosophila enhanced nearly 3.5-fold and 4-fold than that of normal mice and drosophila, respectively. More importantly, pathogenesis analysis revealed that elevated Cu(2+) led to changes in factors closely associated with AD, such as the increasing of reactive oxygen species(ROS), the aggregation of amyloid-β protein (Aβ) and nerve cell cytotoxicity. These findings could promote the understanding of the roles between Cu(2+) and AD.
作者机构：
[Jiang, Wujiu; Tan, Yuxing; Zhang, Zhijian; Ni, Penghui] Hengyang Normal Univ, Key Lab Funct Met Organ Cpds Hunan Prov, Key Lab Organomet New Mat,Coll Chem & Mat Sci, Coll Hunan Prov,Hunan Prov Engn Res Ctr Monitorin, Hengyang 421008, Hunan, Peoples R China.
通讯机构：
[Yuxing Tan] K;Key Laboratory of Functional Metal-Organic Compounds of Hunan Province, Key Laboratory of Organometallic New Materials, College of Hunan Province, Hunan Provincial Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of XiangJiang River, College of Chemistry and Materials Science, Hengyang Normal University , Hengyang, Hunan 421008, China
关键词：
DNA interaction study;anticancer activity;apoptosis;crystal structure;organotin derivative;synthesis
摘要：
Fourteen new organotin(IV) complexes were successfully synthesized and characterized by elemental analyses, Fourier transform infrared spectroscopy (FT-IR), multinuclear (1H, 13C, and 119Sn) NMR spectroscopy, high-resolution mass spectrometry (HRMS), and X-ray single-crystal techniques. Crystallographic data showed that the complexes 1b, 2b, 3b, and 5b were macrocyclic compounds, 4b exhibited a one-dimensional spiral chain structure with distorted trigonal bipyramidal geometry, other complexes were centrosymmetric dimers, and there was an Sn2O2 four-membered ring in the middle of the molecule. In-vitro anticancer activity against the three human tumor cell lines NCI-H460, MCF-7, and HepG2 was studied, and the dibutyltin complex 5a is a more potent antitumor agent than other complexes and cisplatin. Cell apoptosis study of 5a with the highest activity on HepG2 cancer cell lines was done by flow cytometry; it was shown that the antitumor activity of 5a was related to apoptosis, and it inhibited proliferation by blocking cells in the G2/M phase. The single-cell gel electrophoresis assay results show that 5a induces DNA damage. 5a interacts with ct-DNA by intercalating the mode of interaction. UV–visible absorption spectrometry, fluorescence competitive, viscosity measurements, and gel electrophoresis results also support the intercalative mode of interaction for 5a with DNA.
Fourteen organotin(IV) complexes were synthesized by one-pot microwave irradiation. The complex 5a exhibited high activity and selectivity for inhibiting the HepG2 cell line. And it causes DNA damage and induces cell cycle arrest at G2/M phase and apoptosis.
作者机构：
[Gu, Biao] Hunan Provincial Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China. Electronic address: biaogu@hynu.edu.cn;[Liu, Mengqin; Ye, Xinrong] Hunan Provincial Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China;[Long, Jiumei] College of Life Sciences and Environment, Hengyang Normal University, Hengyang 421008, PR China;[Xu, Zhifeng] Hunan Provincial Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China. Electronic address: xuzhifenghwl@163.com;[Shen, Youming] College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Changde 415000, PR China. Electronic address: ymshen79@huas.edu.cn
通讯机构：
[Biao Gu; Zhifeng Xu] H;[Youming Shen] C;Hunan Provincial Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China<&wdkj&>College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Changde 415000, PR China
摘要：
Nitric oxide (NO), an essential biological messenger molecule, participates in various physiological and pathological processes. The sensitive and specific detection of NO is of great significance for understanding the biological function of NO. Here, we synthesized a fluorescent probe (Rho-NO) for highly selective detection of NO both in vitro and in vivo. The high selectivity of Rho-NO is attributed to the fact that NO is easily replaced by electron donor amino group to form N-nitrosation products, causing rhodamine spiro ring open and fluorescence emit. Rho-NO showed a good linear response to NO (0-100 mu M) with a low detection limit (0.06 mu M). Importantly, it exhibited excellent specificity for NO detection in human serum and was also applied for imaging NO in living cells and inflammatory model of zebrafish. This work proves the potential of Rho-NO in pathological research and disease diagnosis. (C) 2021 Elsevier B.V. All rights reserved.
通讯机构：
[Biao Gu; Siping Tang] K;Key Laboratory of Chemical Sensing and Catalysis, Hengyang Key Laboratory of New Detection Technology and Biological Agents of Animal Microorganism, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China
作者机构：
[Tang, Siping; Gu, Biao; He, Shihui] Hengyang Normal Univ, Coll Chem & Mat Sci, Coll Hunan Prov, Key Lab Funct Organometall Mat, Hengyang 421008, Peoples R China.;[Li, Haitao; Wu, Cuiyan] Hunan Normal Univ, Coll Chem & Chem Engn, Key Lab Chem Biol & Tradit Chinese Med Res, Minist Educ, Changsha 410081, Peoples R China.;[Shen, Youming; Zhang, Chunxiang] Hunan Univ Arts & Sci, Coll Chem & Mat Engn, Hunan Prov Key Lab Water Treatment Funct Mat, Changde 415000, Peoples R China.
通讯机构：
[Siping Tang; Haitao Li] K;[Youming Shen] H;Hunan Provincial Key Laboratory of Water Treatment Functional Materials, College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Changde 415000, PR China<&wdkj&>Key Laboratory of Functional Organometallic Materials of College of Hunan Province, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China<&wdkj&>Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, PR China
关键词：
Fast response;Fluorescent probe;Imaging;Lysosome-targetable;Peroxynitrite
摘要：
Peroxynitrite (ONOO-) plays important roles in many pathophysiological processes and its subcellular detection draws increasing attention. In this study, we designed and prepared a novel lysosometargetable fluorescent probe (E)-2-(benzo[d]thiazol-2-yl)-4-methyl-6-((morpholinoimino)methyl)phe nol (BMP) for selective detection of ONOO- in living systems by incorporating a reactive morpholino hydrazone as new ONOO- response site into a benzothiazole derivative as fluorophore. After reaction with ONOO-, an obvious fluorescence increase (83-fold) was observed accompanied with distinct dual colorimetric and fluorescence changes. Probe BMP displayed the merits of fast response (<3 s), ultrasensitivity (LOD = 6 nM) and high selectivity towards ONOO- over other physiological species including ROS/RNS. Most importantly, the probe was capable of imaging ONOO- in lysosomes of living cells with good cell permeation and negligible cytotoxicity. Therefore, this research provides an effective tool to study the functions of ONOO- in lysosomes. (C) 2021 Elsevier B.V. All rights reserved.
期刊：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2021年253:119561 ISSN：1386-1425
通讯作者：
Biao Gu<&wdkj&>Youming Shen
作者机构：
[Shen, Youming; Liu, Qingheng; Zhang, Chunxiang] Hunan Univ Arts & Sci, Prov Engn Res Ctr Electroplating Wastewater Reuse, Hunan Prov Cooperat Innovat Ctr Construct & Dev D, Coll Chem & Mat Engn,Hunan Prov Key Lab Water Tre, Changde 415000, Peoples R China.;[Liu, Mengqin; Gu, Biao; Han, Lujiao] Hengyang Normal Univ, Coll Chem & Mat Sci, Key Lab Funct Organometall Mat Coll Hunan Prov, Hengyang 421008, Peoples R China.
通讯机构：
[Biao Gu] K;[Youming Shen] P;Key Laboratory of Functional Organometallic Materials of College of Hunan Province, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China<&wdkj&>Province Engineering Research Center of Electroplating Wastewater Reuse Technology, Hunan Province Cooperative Innovation Center for the Construction & Development of Dongting Lake Ecological Economic Zone, Hunan Provincial Key Laboratory of Water Treatment Functional Materials, College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Changde 415000, PR China
摘要：
Bisulfite (HSO3-) and sulfite (SO32-) are involved in numerous physiological processes of living systems. However, high levels of these substances are often correlated to many diseases. Herein, we designed and synthesized a simple full water-soluble colorimetric and far-red fluorescent probe (E)-1-methyl-4-(2-(1-methylquinolin-1-ium-3-yl)vinyl)quinolin-1-ium iodide trifluoromethanesulfonate (DQ) for HSO3-/SO32- detection by coupling 1,4-dimethylquinolinium with 3-quinolinium carboxaldehyde for the first time. The probe DQ showed high selectivity for HSO3- detection via a 1,4-nucleophilic addition reaction with distinct color changes from colorless to purple-red and remarkable far-red fluorescence enhancement in pure aqueous solutions. Specifically, the probe displayed a fast response (<15 s) for bisulfite, which renders it suitable for real time detection of HSO3-. Under the optimized conditions, the far-red fluorescence intensity was linear to the concentrations of HSO3- in the range from 0 to 25 mu M and the detection limit was as low as 0.11 mu M. Additionally, the probe could be applied to sense HSO3- on paper strips, real sample including vermicelli and sugar and image HSO3- in living cells, which indicated that probe DQ has potential application in food samples and living systems. (C) 2021 Elsevier B.V. All rights reserved.
摘要：
The nanohybrid of electrochemically-reduced graphene oxide (ERGO) nanosheets decorated with MnO(2) nanorods (MnO(2) NRs) was modified on the surface of a glassy carbon electrode (GCE). Controlled potential reduction was applied for the reduction of graphene oxide (GO). The characterization was performed by scanning electron microscopy, X-ray diffraction and cyclic voltammetry. Compared with the poor electrochemical response at bare GCE, a well-defined oxidation peak of sunset yellow (SY) was observed at the MnO(2) NRs-ERGO/GCE, which was attributed to the high accumulation efficiency as well as considerable electrocatalytic activity of ERGO and MnO(2) NRs on the electrode surface. The experimental parameters for SY detection were optimized in detail. Under the optimized experiment conditions, the MnO(2) NRs-ERGO/GCE showed good linear response to SY in concentration range of 0.01(-)2.0 muM, 2.0(-)10.0 muM and 10.0(-)100.0 muM with a detection limit of 2.0 nM. This developed method was applied for SY detection in soft drinks with satisfied detected results.
摘要：
Control and detection of sunset yellow is an utmost demanding issue, due to the presence of potential risks for human health if excessively consumed or added. Herein, cuprous oxide-electrochemically reduced graphene nanocomposite modified glassy carbon electrode (Cu(2)O-ErGO/GCE) was developed for the determination of sunset yellow. The Cu(2)O-ErGO/GCE was fabricated by drop-casting Cu(2)O-GO dispersion on the GCE surface following a potentiostatic reduction of graphene oxide (GO). Scanning electron microscope and X-ray powder diffractometer was used to characterize the morphology and microstructure of the modification materials, such as Cu(2)O nanoparticles and Cu(2)O-ErGO nanocomposites. The electrochemical behavior of sunset yellow on the bare GCE, ErGO/GCE, and Cu(2)O-ErGO/GCE were investigated by cyclic voltammetry and second-derivative linear sweep voltammetry, respectively. The analytical parameters (including pH value, sweep rate, and accumulation parameters) were explored systematically. The results show that the anodic peak currents of Cu(2)O-ErGO /GCE are 25-fold higher than that of the bare GCE, due to the synergistic enhancement effect between Cu(2)O nanoparticles and ErGO sheets. Under the optimum detection conditions, the anodic peak currents are well linear to the concentrations of sunset yellow, ranging from 2.0 x 10(-8) mol/L to 2.0 x 10(-5) mol/L and from 2.0 x 10(-5) mol/L to 1.0 x 10(-4) mol/L with a low limit of detection (S/N = 3, 6.0 x 10(-9) mol/L). Moreover, Cu(2)O-ErGO/GCE was successfully used for the determination of sunset yellow in beverages and food with good recovery. This proposed Cu(2)O-ErGO/GCE has an attractive prospect applications on the determination of sunset yellow in diverse real samples.
摘要：
The biosorption characteristics of U(VI) from aqueous solution onto a nonliving aquatic macrophyte, Hydrilla verticillata (dry powder), were investigated under various experimental conditions by using batch methods. Results showed that the adsorption reached equilibrium within 60 min and the experimental data were well fitted by the pseudo-first-order kinetic model. U(VI) adsorption was strongly pH dependent, and the optimum pH for U(VI) removal was 5.5. Isotherm adsorption data displayed good correlation with the Langmuir model, with a maximum monolayer adsorption capacity of 171.52 mg/g. Thermodynamic studies suggested that U(VI) adsorption onto H. verticillata was an exothermic and spontaneous process in nature. Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy indicated that the amino and hydroxyl groups on the algal surface played an important role in U(VI) adsorption. The mechanisms responsible for U(VI) adsorption could involve electrostatic attraction and ion exchange. In conclusion, H. verticillata biomass showed good potential as an adsorption material for the removal of uranium contaminants in aqueous solution.
