Screening and Metabolomic Analysis of Lactic Acid Bacteria-Antagonizing Pseudomonas aeruginosa

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成果类型：

期刊论文

作者：

Li, Jianzhou;Chen, Xiaohua;Xie, Ziyan;Liang, Lin;Li, Anping;...

通讯作者：

Li, AP;Lou, ZX

作者机构：

[Li, AP; Li, Anping; Li, Jianzhou] Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Peoples R China.

[Chen, Xiaohua; Xie, Ziyan; Li, Jianzhou] Hengyang Normal Univ, Coll Life Sci, Hunan Key Lab Conservat & Utilizat Biol Resources, Hengyang 421008, Peoples R China.

[Chen, Xiaohua; Liang, Lin] Hengyang Normal Univ, Nanyue Coll, Dept Life Sci, Hengyang 421008, Peoples R China.

[Wen, Yuxi; Zhao, Chao] Fujian Agr & Forestry Univ, Coll Marine Sci, Fuzhou 350002, Peoples R China.

[Wen, Yuxi] Univ Vigo, Fac Sci, Dept Analyt & Food Chem, Nutr & Bromatol Grp, Orense 32004, Spain.

通讯机构：

[Li, AP ] C

[Lou, ZX ] J

Cent South Univ Forestry & Technol, Coll Food Sci & Engn, Changsha 410004, Peoples R China.

Jiangnan Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, Wuxi 214122, Peoples R China.

语种：

英文

关键词：

lactic acid bacteria;Pseudomonas aeruginosa;metabolomic analysis

期刊：

Foods

ISSN：

2304-8158

年：

2023

卷：

期：

页码：

2799-

DOI：

10.3390/foods12142799

基金类别：

This research was funded by the Hunan Provincial National Science Foundation of China (No. 2023JJ30095, No. 2019JJ50014) and the National Natural Science Foundation of China (No. 31601444).

机构署名：

本校为其他机构

院系归属：

生命科学与环境学院

南岳学院

摘要：

Pseudomonas aeruginosa is a conditional Gram-negative pathogen that produces extracellular virulence factors that can lead to bloodstream invasion, severely harm tissues, and disseminate bacteria, ultimately leading to various diseases. In this study, lactic acid bacteria (LAB) with strong antagonistic ability against P. aeruginosa were screened, and the regulatory mechanism of LAB against P. aeruginosa was evaluated. The results showed that the three selected LAB strains had strong inhibition ability on the growth, biofilm formation, and pyocyanin expression of P. aeruginosa and a promoting e...

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Screening and Metabolomic Analysis of Lactic Acid Bacteria-Antagonizing Pseudomonas aeruginosa

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