The surface characteristics of chitosan modified PSt-GMA microspheres influenced the interactions and properties of immobilized pepsin

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成果类型：

期刊论文

作者：

Peng, Gang;Meng, Xu;Wang, Bin;Liu, Bailing*;Chen, Hualin

通讯作者：

Liu, Bailing

作者机构：

[Peng, Gang] Hengyang Normal Univ, Dept Chem & Mat Sci, Hengyang 421008, Peoples R China.

[Peng, Gang] Hengyang Normal Univ, Key Lab Funct Organometall Mat, Hunan Prov Coll, Hengyang 421008, Peoples R China.

[Chen, Hualin; Peng, Gang; Meng, Xu; Liu, Bailing; Wang, Bin] Chinese Acad Sci, Chengdu Inst Organ Chem, Chengdu 610041, Sichuan, Peoples R China.

[Liu, Bailing] Chinese Acad Sci, Chengdu Inst Organ Chem, Renminnan Rd 9, Chengdu 610041, Sichuan, Peoples R China.

通讯机构：

[Liu, Bailing] C

Chinese Acad Sci, Chengdu Inst Organ Chem, Renminnan Rd 9, Chengdu 610041, Sichuan, Peoples R China.

语种：

英文

关键词：

pepsin immobilization;PSt-GMA microsphere;stabilization;enzymatic activity;Chitosan modified microsphere

期刊：

JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY

ISSN：

1060-1325

年：

2015

卷：

期：

页码：

20-29

DOI：

10.1080/10601325.2014.976745

基金类别：

The authors gratefully acknowledge the financial support provided by the National Natural Science Foundation of China (200974111).

机构署名：

本校为第一机构

院系归属：

化学与材料科学学院

摘要：

The surface characteristics of carriers outstandingly influence the application of immobilized enzymes. Because of its biocompatible and multi-functional groups, chitosan was introduced into poly(styrene-co-glycidyl methacrylate) (PSt-GMA) microspheres with/without spacer-arms. Pepsin was immobilized onto these microspheres by a simple and mild process, and then its enzymatic activity was evaluated. As for the different modified microspheres, the interactions between the carrier and enzyme molecules would be different, influencing the immobiliz...

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The surface characteristics of chitosan modified PSt-GMA microspheres influenced the interactions and properties of immobilized pepsin

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