期刊论文

Tang, SP;Zhang, YY

英文

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

1386-1425

2022

270

120728

10.1016/j.saa.2021.120728

CRediT authorship contribution statement Qinghai Tang: Conceptualization, Methodology, Writing – original draft, acquisition. Peijuan Li: Investigation, Visualization, Data curation, Writing – original draft. Zile Zhou: Methodology, Formal analysis. Qiujun Lu: Formal analysis. Biao Gu: Methodology, Formal analysis. Siping Tang: Conceptualization, Resources, Writing – review & editing, acquisition. Youyu Zhang: Conceptualization, Resources, Writing – review & editing, acquisition. Acknowledgements This work was supported by the funding from the National Natural Science Foundation of China (Grant No. 21977028, 21874042 and 21907026), Excellent Youth Project of Hunan Education Department (17B041), and Discipline group construction project of Hengyang Normal University (No. 18XKQ07).

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Nitric oxide (NO), an essential biological messenger molecule, participates in various physiological and pathological processes. The sensitive and specific detection of NO is of great significance for understanding the biological function of NO. Here, we synthesized a fluorescent probe (Rho-NO) for highly selective detection of NO both in vitro and in vivo. The high selectivity of Rho-NO is attributed to the fact that NO is easily replaced by electron donor amino group to form N-nitrosation products, causing rhodamine spiro ring open and fluorescence emit. Rho-NO showed a good linear response ...