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Modulatory Effects of Lactarius hatsudake on Obesity and Gut Microbiota in High-Fat Diet-Fed C57BL/6 Mice

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成果类型:
期刊论文
作者:
Zhu, Hanyu;Hou, Tao
通讯作者:
Hou, T
作者机构:
[Zhu, Hanyu] Hengyang Normal Univ, Coll Life Sci, Hengyang 421000, Peoples R China.
[Hou, T; Hou, Tao] Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Peoples R China.
通讯机构:
[Hou, T ] H
Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Peoples R China.
语种:
英文
关键词:
Lactarius hatsudake;biochemical index;gut microbiota;correlation analysis;obesity
期刊:
Foods
ISSN:
2304-8158
年:
2024
卷:
13
期:
6
页码:
948-
基金类别:
Conceptualization, H.Z. and T.H.; methodology, H.Z. and T.H.; validation, T.H.; investigation, H.Z.; resources, T.H.; data curation, H.Z.; writing—original draft preparation, H.Z.; writing—review and editing, T.H.; project administration, T.H.; funding acquisition, H.Z. All authors have read and agreed to the published version of the manuscript. This research was funded by the Natural Science Foundation of Hunan Province (grant number 2022JJ40013) and Scientific Research Foundation of Hunan Provincial Education Department (grant number 23B0667).
机构署名:
本校为第一机构
摘要:
Lactarius hatsudake (LH), a great wild endemic fungus, contains rich nutritional components with medicinal properties. The effects of LH on body weight, liver weight, liver injury, blood lipids, and gut microbiota in C57BL/6 mice fed a high-fat diet (HFD) for 8 weeks was examined in this research. Though there was no clear impact on weight loss, the findings indicate that LH treatment effectively decreased liver damage caused by HFD, as well as lowered serum total cholesterol, triacylglycerol, and low-density lipoprotein cholesterol levels. Additionally, it positively influenced gut microbiota...

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