The Mixed-ligands complexes of L-glutamic acid and L-arginine with Cu( II) was synthesized. The composition of the complex was determined by chemical analysis, element analysis and thermal gravity analysis. By solution calorimetry in a reaction calorimeter at 298.2 K, the dissolution enthalpy for the reactant, CuSO4. 5H(2)O(s), L-Glutamic acid (s) and L-Arginine (s), and the product, Cu . Glu . Arg . SO4 . 5H(2)O(s), were determined. They were dissolved in 2 mol . L-1 H2SO4 Solution, respectively. A themochernistry cycle was designed, to obtain the coordinate reaction enthalpy change, Delta H-...