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Dual Ratiometric Single-Molecule Theranostic Probes for Photothermal Therapy and Real-Time Quantitative Evaluation of Therapeutic Efficacy In Vivo

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成果类型:
期刊论文
作者:
Zhang, Shuping;Liu, Xingyue;Jiang, Bang-Ping;Ji, Shi-Chen;Chen, Hua*;...
通讯作者:
Chen, Hua;Shen, XC
作者机构:
[Liu, Xingyue; Shen, Xing-Can; Jiang, Bang-Ping; Chen, Hua; Zhang, Shuping; Chen, H; Ji, Shi-Chen] Guangxi Normal Univ, Sch Chem & Pharmaceut Sci, Key Lab Chem & Mol Engn Med Resources, Guangxi Key Lab Chem & Mol Engn Med Resources,Mini, Guilin 541004, Peoples R China.
[Zhang, Shuping] Hengyang Normal Univ, Key Lab Funct Organometall Mat, Coll Chem & Mat Sci, Coll Hunan Prov, Hengyang 421008, Peoples R China.
通讯机构:
[Shen, XC ; Chen, H] G
Guangxi Normal Univ, Sch Chem & Pharmaceut Sci, Key Lab Chem & Mol Engn Med Resources, Guangxi Key Lab Chem & Mol Engn Med Resources,Mini, Guilin 541004, Peoples R China.
语种:
英文
期刊:
Analytical Chemistry
ISSN:
0003-2700
年:
2025
卷:
97
期:
25
页码:
13637–13645
基金类别:
Education Department of Hunan Province [22467004, 22167004]; National Natural Science Foundation of China [2023GXNSFFA026014]; Natural Science Foundation of Guangxi; BAGUI Scholar Program of Guangxi; BAGUI Youth Elite Talent Training Project of Guangxi [202410602056]; National Training Program of Innovation and Entrepreneurship for undergraduates [2023QD21]; Hengyang Normal University [24B0644, 23A0519]; Scientific Research of Hunan Provincial Department of Education [YCBZ2022070, S202410602147]; Innovation Project of Guangxi Graduate Education
机构署名:
本校为其他机构
院系归属:
化学与材料科学学院
摘要:
Tracking the quantitative evaluation of therapeutic efficiency in tumors is essential for the precision management of cancer patients. Theranostic probes, which integrate diagnostic molecular imaging and therapeutic capabilities into a single entity, can be used to monitor the treatment process and reflect the therapeutic effect. However, current theranostic probes lack precise quantitative evaluations in vivo due to the use of single-wavelength imaging during tumor therapy. Here we present a portal library of dual ratiometric single-molecule theranostic probes for precise tumor therapy throug...

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