fl-Galactosidase is closely related to primary ovarian cancer and highly expressed in metastatic ovarian cancer. Therefore, the development of effective tool for in situ detecting fl-gal is urgently needed for further studies in ovarian cancer. Inspired by the advantages of near-infrared (NIR) fluorescence imaging, a NIR fluorescent probe (DCM-CHO-beta gal) with improved near-infrared fluorescence emission and detection performance was reasonably designed for the quantification and visualization of fl-gal, employing structurally modified dicyanobenzopyran derivative (DCM-CHO-OH) as fluorophore...
