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Catalyst- and Additive-Free Method for the Synthesis of 2-Substituted Benzothiazoles from Aromatic Amines, Aliphatic Amines, and Elemental Sulfur

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成果类型:
期刊论文
作者:
Zhu, Xiaoming;Zhou, Fengru;Yang, Yuan;Deng, Guobo*;Liang, Yun*
通讯作者:
Deng, Guobo;Liang, Yun
作者机构:
[Yang, Yuan; Zhu, Xiaoming; Deng, Guobo; Liang, Yun; Zhou, Fengru] Hunan Normal Univ, Coll Chem & Chem Engn,Key Lab Chem Biol & Tradit, Minist Educ,Key Lab Assembly & Applicat Organ Fun, Natl & Local Joint Engn Lab New Petrochem Mat & F, Changsha 410081, Hunan, Peoples R China.
[Zhu, Xiaoming] Hengyang Normal Univ, Coll Chem & Mat Sci, Hunan Prov Univ Key Lab Funct Organometall Mat, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421008, Hunan, Peoples R China.
通讯机构:
[Deng, GB; Liang, Y] H
Hunan Normal Univ, Coll Chem & Chem Engn,Key Lab Chem Biol & Tradit, Minist Educ,Key Lab Assembly & Applicat Organ Fun, Natl & Local Joint Engn Lab New Petrochem Mat & F, Changsha 410081, Hunan, Peoples R China.
语种:
英文
期刊:
ACS OMEGA
ISSN:
2470-1343
年:
2020
卷:
5
期:
22
页码:
13136-13147
基金类别:
G.D., Y.L., and Y.Y. received funding from the National Natural Science Foundation of China (nos. 21602057, 21572051, 21901071, and 21971061), the Opening Fund of the Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China), and Hunan Normal University (nos. KLCBTCMR201707 and KLCBTCMR201708), Y.L., Y.Y., and X.Z received funding from the Scientific Research Projects of Education Department of Hunan Province (nos. 18A002, 18K089, and 19B359). Y.L. received funding from the Science and Technology Planning Project of Hunan Province (no. 2018TP1017). X.Z. received funding from Hengyang Normal University (no. 19QD14).
机构署名:
本校为其他机构
院系归属:
化学与材料科学学院
摘要:
Under catalyst-and additive-free conditions, a novel, convenient, environmentally friendly method was developed for the synthesis of 2-substituted benzothiazoles via the three-component one pot reaction from aromatic amines, aliphatic amines, and elemental sulfur. The reaction achieves double C-S and one C-N bond formations via cleavage of two C-N bonds and multiple C-H bonds. Furthermore, the mechanism research shows that DMSO acts as an oxidant in the cycliz...

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