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Construction of a multifunctional bio-probe based on lanthanides for UCL/MR/CT multimodal imaging in vivo

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成果类型:
期刊论文
作者:
Xiang, Lijun;Wang, Chengying;Mao, Yifu;Jiang, Yong;Hu, Zhifeng;...
通讯作者:
Xiang, LJ;Hu, ZF;Mao, YF
作者机构:
[Jiang, Yong; Wang, Chengying; Xiang, Lijun] Anqing Normal Univ, Anqing Forestry Technol Innovat Res Inst, Collaborat Innovat Ctr Targeted Dev Med Resources, Sch Life Sci,Key Lab Biodivers Conservat & Charact, Anqing 246011, Peoples R China.
[Hu, ZF; Hu, Zhifeng; Wang, Yong] Wannan Med Coll, Affliated Hosp 1, Yijishan Hosp, Dept Intervent Therapy, Wuhu, Peoples R China.
[Mao, Yifu; Mao, YF] Hengyang Normal Univ, Coll Phys & Elect Engn, Hengyang 421002, Peoples R China.
通讯机构:
[Hu, ZF ] W
[Mao, YF ] H
[Xiang, LJ ] A
Anqing Normal Univ, Anqing Forestry Technol Innovat Res Inst, Collaborat Innovat Ctr Targeted Dev Med Resources, Sch Life Sci,Key Lab Biodivers Conservat & Charact, Anqing 246011, Peoples R China.
Wannan Med Coll, Affliated Hosp 1, Yijishan Hosp, Dept Intervent Therapy, Wuhu, Peoples R China.
语种:
英文
关键词:
in vivo multimodal bioimaging;lanthanide fluorides;nanobio-probe
期刊:
BIOMEDICAL MATERIALS
ISSN:
1748-6041
年:
2025
卷:
20
期:
2
页码:
025005
基金类别:
2024 College Student' Innovation and Entrepreneurship Training Program of Anhui Province [2023AH050510, 2022AH051026]; Key project of Natural Science Research in Universities of Anhui Province [Wxn202412]; Open Fund Projects of the Province Key Laboratory of the Biodiversity Study and Ecology Conservation in Sounthwest Anhui [2023HSKFJJ022]; Key Laboratory of Micro-nano Energy Materials and Application Technologies, University of Hunan Province [S202410372029]; College Student' Innovation and Entrepreneurship Training Program of Anhui Province [X202410372053]; College Student' Innovation and Entrepreneurship Training Program of Anqing Normal University [2023AH030072]; Natural Science Research Project of Anhui Education Department
机构署名:
本校为通讯机构
院系归属:
物理与电子工程学院
摘要:
Multimodal bioimaging is beneficial for clinical diagnosis and research due to the provision of comprehensive diagnostic information. However, the design of multifunctional bio-probes aggregating multiple bioimaging functions is greatly challenging. In this study, a multifunctional bio-probe based on lanthanide-based nanomaterials Sr(2)GdF(7): Yb(3+)/Er(3+)/Tm(3+)(abbreviated as SGF) was developed forin vivomultimodal imaging by co-adopting apropos lanthanides and tuning their molar ratio. The experimental results indicate that SGF incorporates multiple excellent properties, such as 10 nm smal...

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