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Comparative proteomics reveals biochemical changes in Salvia miltiorrhiza Bunge during sweating processing

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成果类型:
期刊论文
作者:
Guo, Xiaohu;Meng, Xiaoxi;Li, Yan;Qu, Changqing;Liu, Yingying;...
通讯作者:
Shihai Xing<&wdkj&>Weimin Jiang
作者机构:
[Guo, Xiaohu; Xing, Shihai; Yao, Xiaoyan; Cao, Mengyang; Wu, Jing; Peng, Daiyin; Peng, Huasheng; Meng, Fei] Anhui Univ Chinese Med, Coll Pharm, Hefei 230012, Peoples R China.
[Meng, Xiaoxi] Univ Minnesota, Dept Hort Sci, Minneapolis, MN 55108 USA.
[Jiang, Weimin; Li, Yan] Hengyang Normal Univ, Coll Life Sci & Environm, Hunan Key Lab Conservat & Utilizat Biol Resources, Hengyang 421008, Peoples R China.
[Qu, Changqing] Fuyang Normal Univ, Engn Technol Res Ctr Antiaging, Chinese Herbal Med, Fuyang 236037, Peoples R China.
[Liu, Yingying] Anhui Univ Chinese Med, Coll Humanities & Int Educ Exchange, Hefei 230012, Peoples R China.
通讯机构:
[Shihai Xing] C
[Weimin Jiang] H
College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China<&wdkj&>Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement, Hefei, 230038, China<&wdkj&>Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, 230012, China<&wdkj&>Hunan Key Laboratory for Conservation and Utilization of Biological Resources in the Nanyue Mountainous Region, College of Life Sciences and Environment, Hengyang Normal University, Hengyang, 421008, China
语种:
英文
关键词:
cytochrome P450;dicarboxylic acid;glyoxylic acid;ligase;linoleic acid;oxidoreductase;peroxidase;plant protein;proteome;proteome;Article;biochemical analysis;bioinformatics;biosynthesis;cell wall;cellular distribution;comparative proteomics;controlled study;data base;enzyme activity;functional enrichment analysis;gene set enrichment analysis;high performance liquid chromatography;KEGG;metabolite;nonhuman;pathogenesis;pathway enrichment analysis;plant root;plant sweating;processing;protein analysis;protein domain;protein expression;Salvia miltiorrhiza;TMT labeling;chemistry;Chinese medicine;metabolism;proteomics;sweating;Medicine, Chinese Traditional;Plant Roots;Proteome;Proteomics;Salvia miltiorrhiza;Sweating
期刊:
Journal of Ethnopharmacology
ISSN:
0378-8741
年:
2022
卷:
293
页码:
115329
基金类别:
This work was supported by the NSF of Anhui Province (Grant No. 1908085MH268 ), Key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources (Grant No. 2060302 ), Natural Science Foundation of China (Grant No. 31800169 ), Anhui University Collaborative Innovation Project (Grant No. GXXT-2019-049 ), and Foundation of Hunan Key Laboratory for Conservation and Utilization of Biological Resources in the Nanyue Mountainous Region (Grant No. NY20K04 ).
机构署名:
本校为其他机构
院系归属:
生命科学与环境学院
摘要:
Ethnopharmacological relevance: Salvia miltiorrhiza Bunge is a bulk medicinal material used in traditional Chinese medicine, that can cure cardiovascular diseases, neurasthenia, and other conditions. Sweating is a frequently used method of processing S. miltiorrhiza for medical applications. We previously demonstrated changes to the metabolic profile of linoleic acid, glyoxylate, and dicarboxylate after Sweating. However, this alteration has not been explained at the molecular level. Materials and methods: Fresh roots of Salvia miltiorrhiza Bun...

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