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Synthesis of Anti-Epileptic Drug Retigabine Combined with Clinical Therapeutic Effect

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成果类型:
期刊论文
作者:
Zeng, Zhiwen*;Li, Xiang;Zhang, Fuxing
通讯作者:
Zeng, Zhiwen
作者机构:
[Zeng, Zhiwen] Hunan Polytech Environm & Biol, Dept Basic Courses, Hengyang 421005, Hunan, Peoples R China.
[Li, Xiang] Hunan Polytech Environm & Biol, Dept Med & Tech, Hengyang 421005, Hunan, Peoples R China.
[Zhang, Fuxing] Hengyang Normal Univ, Dept Chem & Mat Sci, Hengyang 421008, Hunan, Peoples R China.
通讯机构:
[Zeng, Zhiwen] H
Hunan Polytech Environm & Biol, Dept Basic Courses, Hengyang 421005, Hunan, Peoples R China.
语种:
英文
关键词:
Retigabine Synthesis;Clinical Response;Epilepsy
期刊:
INVESTIGACION CLINICA
ISSN:
0535-5133
年:
2020
卷:
61
期:
3
页码:
1148-1155
基金类别:
Scientific Research Project of Education Bureau of Hunan Province [15C0472]; Science and Technology Project of Hengyang [2015KS27]
机构署名:
本校为其他机构
院系归属:
化学与材料科学学院
摘要:
Retigabine is a new type of drug widely used in the treatment of epilepsy and other symptoms. It is mainly used for adjuvant treatment of partial seizures in adults with refractory epilepsy. There are many synthetic processes of retigabine. However, retigabine can cause fatigue, dizziness, vertigo and even neurasthenia and hallucinations during clinical treatment. This article combines the patient's clinical response to develop the synthetic scheme of retigabine. And according to the side effects of adjuvant retigabine treatment. This article summarizes the various synthetic methods of retigab...

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