期刊论文

Curative effect of lacrimal point embolization on moderate mixed xerophthalmia

中文

中国现代医学杂志

1005-8982

2017

27

16

58-61

10.3969/j.issn.1005-8982.2017.16.012

湖南省卫生计划生育委员会基金(No:B2015-57)；

本校为其他机构

目的观察泪小点栓塞术对中度混合型干眼患者眼部症状体征及炎症因子的影响,评价泪小点栓塞术对中度混合型干眼的疗效。方法对中度混合型干眼患者行泪小点栓塞术。对患者术前、术后30和60 d的OSDI评分、泪膜破裂时间(TBUT)、泪液分泌实验(未表面麻醉的Schirmer I)以及角膜荧光染色评分进行评估,并且测量泪液中炎症因子IL-1β、金属蛋白酶9(MMP-9)及TNF-α的表达,比较上述指标的变化。结果34例(68眼)中度混合型干眼患者术后与术前相比,干眼患者OSDI评分、角膜荧光染色评分下降,差异有统计学意义(P0.05);泪液中炎症因子IL-1β,MMP-9及TNF-α的水平均出现了不同程度的降低,差异有统计学意义(P

Objective To observe the effect of lacrimal point embolization on eye symptoms and signs and inflammatory factors in patients with moderate mixed xerophthalmia, and to evaluate the curative effect. Methods Lacrimal punctum embolization was applied to the patients with moderate mixed dry eyes. OSDI scores, tear film break-up time (TBUT), Schirmer test (not table linen Schirmer I), corneal fluorescein staining scores were assessed before operation and 30 and 60 d after operation. The inflammatory factors IL-1β, matrix metalloproteinase-9 (MMP-9)...