Systematic qualitative proteome-wide analysis of lysine malonylation profiling in Platycodon grandiflorus

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成果类型：

期刊论文

作者：

Yang, Qingshan;Xu, Shaowei;Jiang, Weimin;Meng, Fei;Wang, Shuting;...

通讯作者：

Liu, Juan;Xing, SH

作者机构：

[Yang, Qingshan; Wang, Shuting; Liu, Juan; Xing, SH; Peng, Daiyin; Xing, Shihai; Xu, Shaowei; Meng, Fei] Anhui Univ Chinese Med, Coll Pharm, Hefei 230012, Peoples R China.

[Jiang, Weimin] Hengyang Normal Univ, Coll Life Sci & Environm, Hunan Key Lab Conservat & Utilizat Biol Resources, Hengyang 421008, Hunan, Peoples R China.

[Xing, SH; Peng, Daiyin; Xing, Shihai; Meng, Fei] Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei 230012, Peoples R China.

[Sun, Zongping] Fuyang Normal Univ, Engn Technol Res Ctr Antiaging, Chinese Herbal Med, Fuyang 236037, Peoples R China.

[Xing, SH; Xing, Shihai; Chen, Na] Hefei Comprehens Natl Sci Ctr, Joint Res Ctr Chinese Herbal Med Anhui IHM, Bozhou 236814, Peoples R China.

通讯机构：

[Liu, J; Xing, SH ] A

Anhui Univ Chinese Med, Coll Pharm, Hefei 230012, Peoples R China.

Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei 230012, Peoples R China.

Hefei Comprehens Natl Sci Ctr, Joint Res Ctr Chinese Herbal Med Anhui IHM, Bozhou 236814, Peoples R China.

语种：

英文

关键词：

Platycodon grandiflorus;Lysine malonylation;Saponin biosynthesis;Polysaccharide biosynthesis;Heavily-malonylated

期刊：

Amino Acids

ISSN：

0939-4451

年：

2025

卷：

期：

页码：

1-14

DOI：

10.1007/s00726-024-03432-3

基金类别：

This work was supported by Key Natural Science Research Projects in Anhui Universities (No. 2022AH050461, No. KJ2019A0453 and KJ2018A0275), Open Project of Provincial and Ministerial Scientific Research Platform, Project from Joint Research Center for Chinese Herbal Medicine of Anhui of IHM (yjzx2023001), Scientific Research Team Program of Anhui Colleges and Universities (Grant No. 2022AH010036), Fuyang Normal University (No. FSKFKT010D) and Anhui University Collaborative Innovation Project (Grant No. GXXT-2019-043, Grant No. GXXT-2019-049).

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院系归属：

生命科学与环境学院

摘要：

In recent years, it was found that lysine malonylation modification can affect biological metabolism and play an important role in plant life activities. Platycodon grandiflorus, an economic crop and medicinal plant, had no reports on malonylation in the related literature. This study qualitatively introduces lysine malonylation in P. grandiflorus. A total of 888 lysine malonylation-modified proteins in P. grandiflorus were identified, with a total of 1755 modification sites. According to the functional annotation, malonylated proteins were closely related to catalysis, binding, and other reac...

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Systematic qualitative proteome-wide analysis of lysine malonylation profiling in Platycodon grandiflorus

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