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Syntheses, Crystal Structures and Biological Activity of the 1D Chain Benzyltin Complexes Based on 2-Oxo-Propionic Acid Benzoyl Hydrazone

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成果类型:
期刊论文
作者:
Tan, Yu-Xing;Zhang, Zhi-Jian;Feng, Yong-Lan;Yu, Jiang-Xi;Zhu, Xiao-Ming;...
通讯作者:
Jiang, Wu-Jiu
作者机构:
[Zhang, Fu-Xing; Jiang, Wu-Jiu; Kuang, Dai-Zhi; Tan, Yu-Xing; Feng, Yong-Lan; Zhang, Zhi-Jian; Yu, Jiang-Xi; Zhu, Xiao-Ming] Hengyang Normal Univ, Coll Hunan Prov, Coll Chem & Mat Sci, Key Lab Funct Organometall Mat, Hengyang 421008, Hunan, Peoples R China.
通讯机构:
[Jiang, Wu-Jiu] H
Hengyang Normal Univ, Coll Hunan Prov, Coll Chem & Mat Sci, Key Lab Funct Organometall Mat, Hengyang 421008, Hunan, Peoples R China.
语种:
英文
关键词:
Bioactivity;Cell culture;Chains;Chemical compounds;Complexation;Diseases;Nuclear magnetic resonance spectroscopy;Organometallics;Single crystals;Synthesis (chemical);Thymus;Tin;Anti-tumor activities;Chemical optimizations;Electrostatic attractions;Fluorescent probes;Human cancer cells;Hydrazones;Organotins;X-ray single-crystal diffraction;Crystal structure
期刊:
Journal of Inorganic and Organometallic Polymers and Materials
ISSN:
1574-1443
年:
2017
卷:
27
期:
1
页码:
342-352
基金类别:
The project was supported by the Scientific and Technological Projects of Hunan Province of China (No. 2015JC3060), Hunan Provincial Natural Science Foundation of China (No. 2016JJ4008) and The Innovation Platform Open Fund Project of Hunan Provincial Education Department of China (No. 16K011).
机构署名:
本校为第一且通讯机构
院系归属:
化学与材料科学学院
摘要:
Two new 1D Chain benzyltin complexes {[C6H4(O)C=N–N=C(Me)COO](CH3OH)(C6H5CH2)2Sn}n (1), {[C6H4(O)C–NH–N=C(Me)COO](C6H5CH2)3Sn}n (2) were synthesized by the reactions of 2-oxo-propionic acid benzoyl hydrazone with dibenzyltin dichloride or tribenzyltin chloride, respectively. The two complexes were characterized by FT-IR, 1H, 13C and 119Sn NMR spectra, elemental analysis, X-ray single crystal diffraction and TGA. In vitro antitumor activities of both complexes were evaluated by the 3-(4,5-dimethylthiazoly-2-yl)-2,5-diphenyltetrazolium bromide...

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