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Synthesis, crystal structure and anticancer activity of the dibutyltin(IV)oxide complexes containing substituted salicylaldehyde-o-aminophenol Schiff base with appended donor functionality

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成果类型:
期刊论文
作者:
Zhang, Zhi-Jian;Zeng, Hui-Ting;Liu, Yang;Kuang, Dai-Zhi;Zhang, Fu-Xing;...
通讯作者:
Tan, Yu-Xing;Jiang, Wu-Jiu
作者机构:
[Tan, Yu-Xing; Jiang, WJ; Zhang, Fu-Xing; Jiang, Wu-Jiu; Kuang, Dai-Zhi; Liu, Yang; Zhang, Zhi-Jian] Hengyang Normal Univ, Coll Chem & Mat Sci, Univ Hunan Prov, Key Lab Funct Met Organ Cpds Hunan Prov,Key Lab F, Hengyang 421008, Hunan, Peoples R China.
[Zeng, Hui-Ting] Sch Med Technol, Hengyang, Hunan Polytech Environm & Biol, Hengyang, Hunan, Peoples R China.
通讯机构:
[Tan, YX; Jiang, WJ] H
Hengyang Normal Univ, Coll Chem & Mat Sci, Univ Hunan Prov, Key Lab Funct Met Organ Cpds Hunan Prov,Key Lab F, Hengyang 421008, Hunan, Peoples R China.
语种:
英文
关键词:
anticancer activity;crystal structure;organotin;Schiff base;synthesis
期刊:
Inorganic and Nano-Metal Chemistry
ISSN:
2470-1556
年:
2018
卷:
48
期:
10
页码:
486-494
基金类别:
This work was supported by the Hunan Provincial Natural Science Foundation of China (Nos. 2017JJ3003, 2016JJ5004) and Foundation of Key Laboratory of Functional Metal-Organic Compounds of Hunan Province (No. MO18K01).
机构署名:
本校为第一且通讯机构
院系归属:
化学与材料科学学院
摘要:
Schiff base butyltin complexes C1 ∼ C3 have been synthesized via the reaction of dibutyltin oxide with the substituted salicylaldehyde-o-aminophenol Schiff base ligands (L1 ∼ L3), respectively. The complexes have been characterized by elemental analysis, IR, UV-Vis, 1 H NMR, 13C NMR spectra and the crystal structures have been determined by X-ray diffraction. The anticancer activity of the Schiff base ligands L1 ∼ L3 and complexes C1 ∼ C3 against five species of cancer cells which are MCF7, Colo205, NCI-H460, Hela and HepG2 were tested resp...

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