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Synthesis, Crystal Structure, and Anticancer Activity of the Dinuclear Dibutyltin Complexes

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成果类型:
期刊论文
作者:
Li, Aodian;Wang, Tiantian;Feng, Yunyun;Qin, Qiqi;Jiang, Wujiu;...
通讯作者:
Wujiu Jiang<&wdkj&>Yuxing Tan
作者机构:
[Jiang, Wujiu; Li, Aodian; Tan, Yuxing; Qin, Qiqi; Feng, Yunyun; Wang, Tiantian] Hengyang Normal Univ, Key Lab Funct Metal Organ Cpds Hunan Prov, Key Lab Organometall New Mat Hunan Prov Engn Res, Coll Chem & Mat Sci, Hengyang 421008, Hunan, Peoples R China.
通讯机构:
[Wujiu Jiang; Yuxing Tan] K
Key Laboratory of Functional Metal-Organic Compounds of Hunan Province, Key Laboratory of Organometallic New Materials, Hunan Provincial Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of XiangJiang River, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang, Hunan, China<&wdkj&>Key Laboratory of Functional Metal-Organic Compounds of Hunan Province, Key Laboratory of Organometallic New Materials, Hunan Provincial Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of XiangJiang River, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang, Hunan, China
语种:
英文
关键词:
dibutyltin;synthesis;crystal structure;anticancer activity
期刊:
Russian Journal of General Chemistry
ISSN:
1070-3632
年:
2022
卷:
92
期:
5
页码:
908-913
基金类别:
This work was supported by the 22nd College students Extracurricular Academic Science and Technology Works Competition Project of Hengyang Normal University (no. 13).
机构署名:
本校为第一机构
院系归属:
化学与材料科学学院
摘要:
Abstract: Dinuclear dibutyltin complexes {[2-O-C6H4(O)C=N-N=C(O)CPh2O](n-Bu2Sn)2}n (C1) and {[2-(3-O-C8H6)(O)C=N-N=C-2-(3-O-C8H6)]2(n-Bu2Sn)2}n (C2) have been synthesized and characterized by IR, 1H, 13C, and 119Sn NMR spectra, HRMS, elemental analysis, and thermal stability analysis. Their crystal structures have been determined by X-ray diffraction. In vitro antitumor activities of both complexes have been evaluated by the CCK8 method against three human cancer cell lines (MCF-7, NCI-H460, and HepG2), and the complexes have exhibited hig...

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