期刊论文

Li, JH;Qian, D;Waterhouse, GIN

英文

Biosensors and Bioelectronics

0956-5663

2025

280

117454

10.1016/j.bios.2025.117454

Acknowledgements This work was financially supported by the Changsha Natural Science Foundation Project (No. kq2402198 ), Natural Science Foundation of Hunan Province ( 2024JJ6098 ), National Natural Science Foundation of China (No. 21505035 , 51874359 , 21171174 ). GINW acknowledges funding support from the MacDiarmid Institute for Advanced Materials and Nanotechnology , as well as the Dodd-Walls Centre for Photonic and Quantum Technologies .

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Dual-mode sensors integrating multifunctional nanozymes are highly sought by the analytical chemistry community. However, rational design of nanozymes containing both metal single atoms (SAs) and atomic clusters (ACs) for dual-mode sensing remains a challenge. Herein, we designed and synthesized a novel Cu-based nanozyme system based on Cu SAs/ACs anchored on a N-doped chitosan-derived carbon support (CuSAs/ACs@NC) using a tandem ion imprinting-pyrolysis-etching strategy. Compared with Cu SAs or Cu nanoparticles on the chitosan-derived carbon s...