期刊论文

The Effect of Long-time and Low-intensity Swimming Exercises on the Expression of Cardiovascular ADM mRNA and RAMP2mRNA in Rats

中文

天津体育学院学报

1005-0000

2005

20

04

5-7,36

10.3969/j.issn.1005-0000.2005.04.002

河南省自然科学基金项目资助（项目编号:0511030100）； 衡阳师范学院青年科学基金（项目编号:2004D28）；

本校为第一机构

目的:探讨运动训练带来心血管系统ADM、RAMP2在mRNA水平上的变化.方法:选用雄性Sprague-Dawley(SD)大鼠随机分为3组,安静对照组(CR,n=8)、运动力竭组(ER,n=8)和运动训练组(TR,n=8)进行饲养训练.RT-pCR测定心尖肌组织和主动脉弓部血管ADM mRNA、RAMP2mRNA的表达水平.结果发现:(1)与安静对照组相比,一次急性有氧力竭游泳运动对大鼠心脏和主动脉ADM和RAMP2的mRNA表达无显著影响;(2)与安静对照组相比,长时期进行低强度的有氧游泳训练能在不同程度上引起心脏ADM和RAMP2的mRNA表达显著上调,反映出长期低强度有氧运动训练后心脏在分子水平上的良好适应;而长时期进行低强度有氧游泳训练对主动脉的影响是...

The main purpose of the research was to survey rats cardiovascular expression of ADM mRNA? RAMP2mRNA after a eight-week swimming training, and then to elucidate elementarily molecular mechanism of exercise-induced adaptation. 24 purebred male Sprague-Dawley rats were divided randomly into three groups: controlled(CR, n=8), exhausted(ER, n=8), trained(TR, n=8). After swimming training left ventricular muscle and main artery arch are extracted, we are inspecting the expression of ADM mRNA, RAMP2mRNA by RT-PCR. The results were shown as follows: 1.Comparing with the controlled group, one time exh...