Lactic acid bacteria exhibit similar antioxidant capacities in Caenorhabditis elegans- and Campylobacter jejuni-infected mice

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期刊论文

作者：

Jin, Xing;He, Yufeng;Liu, Zhenmin*;Zhou, Yonghua*;Chen, Xiaohua;...

通讯作者：

Wang, Gang;Liu, Zhenmin;Zhou, Yonghua

作者机构：

[Chen, Wei; He, Yufeng; Zhao, Jianxin; Wang, Gang; Zhang, Hao; Jin, Xing] Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China.

[Liu, Zhenmin] Bright Daily & Food Co Ltd, State Key Lab Dairy Biotechnol, Shanghai Engn Res Ctr Dairy Biotechnol, Dairy Res Inst, Shanghai 200436, Peoples R China.

[Zhou, Yonghua] Jiangsu Inst Parasit Dis, Key Lab Natl Hlth & Family Planning Commiss Paras, Jiangsu Prov Key Lab Parasite & Vector Control Te, Wuxi 214064, Jiangsu, Peoples R China.

[Chen, Xiaohua] Hengyang Normal Univ, Coll Life Sci & Environm, Hengyang 421008, Peoples R China.

[Chen, Wei; Zhao, Jianxin; Wang, Gang; Zhang, Hao] Jiangnan Univ, Sch Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China.

通讯机构：

[Wang, Gang; Zhou, Yonghua] J

[Liu, Zhenmin] B

Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China.

Bright Daily & Food Co Ltd, State Key Lab Dairy Biotechnol, Shanghai Engn Res Ctr Dairy Biotechnol, Dairy Res Inst, Shanghai 200436, Peoples R China.

Jiangsu Inst Parasit Dis, Key Lab Natl Hlth & Family Planning Commiss Paras, Jiangsu Prov Key Lab Parasite & Vector Control Te, Wuxi 214064, Jiangsu, Peoples R China.

语种：

英文

期刊：

RSC Advances

ISSN：

2046-2069

年：

2020

卷：

期：

页码：

3329-3342

DOI：

10.1039/c9ra06105c

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31671839, 31530056, 31601444, 31301407]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [JUSRP51501]; Priority Academic Program Development of Jiangsu Higher Education Institutions; national.rst-class discipline program of Food Science and Technology [JUFSTR20180102]; Program of Collaborative Innovation Centre of Food Safety and Quality Control in Jiangsu Province; Scienti.c Research Fund of Hunan Provincial Education Department [15B034]

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院系归属：

生命科学与环境学院

摘要：

Caenorhabditis elegans (C. elegans) is increasingly used as a model organism to screen probiotics for ageing research. In this study, a C. elegans lifespan analysis model exposed to H2O2 and juglone (for chronic and acute assays) was used to preselect lactic acid bacteria (LAB) with resistance to oxidative stress. The mechanism of oxidative stress protection was analyzed. Seven out of ten LAB strains screened for namely 427, X13, 9-5, 422, Z5, G14 and H29M-8M demonstrated higher levels of protection to C. elegans, ranging from 70% to 85% survival rate, in comparison to the inactive strains 408...

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Lactic acid bacteria exhibit similar antioxidant capacities in Caenorhabditis elegans- and Campylobacter jejuni-infected mice

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