UPLC/MS-based untargeted metabolomics reveals the changes of metabolites profile of Salvia miltiorrhiza bunge during Sweating processing

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成果类型：

期刊论文

作者：

Cao, Mengyang;Liu, Yingying;Jiang, Weimin;Meng, Xiaoxi;Zhang, Wei;...

通讯作者：

Xing, Shihai

作者机构：

[Zhang, Wei; Peng, Daiyin; Xing, Shihai; Chen, Weidong; Cao, Mengyang] Anhui Univ Chinese Med, Coll Pharm, Room 405,Qianjiang Rd 1, Hefei 230012, Anhui, Peoples R China.

[Peng, Daiyin; Xing, Shihai; Cao, Mengyang] Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei 230012, Peoples R China.

[Liu, Yingying] Anhui Univ Chinese Med, Coll Humanities & Int Educ Exchange, Hefei 230012, Peoples R China.

[Jiang, Weimin] Hengyang Normal Univ, Coll Life Sci & Environm, Hengyang 421008, Hunan, Peoples R China.

[Meng, Xiaoxi] Univ Minnesota, Dept Hort Sci, Minneapolis, MN 55108 USA.

通讯机构：

[Xing, Shihai] A

Anhui Univ Chinese Med, Coll Pharm, Room 405,Qianjiang Rd 1, Hefei 230012, Anhui, Peoples R China.

Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei 230012, Peoples R China.

Anhui Prov Key Lab Res & Dev Chinese Med, Hefei 230012, Peoples R China.

语种：

英文

期刊：

Scientific Reports

ISSN：

2045-2322

年：

2020

卷：

期：

页码：

19524

DOI：

10.1038/s41598-020-76650-w

基金类别：

This work was supported by the NSF of Anhui Province (Grant No. 1908085MH268), Key Natural Science Research Projects in Anhui Universities (Grant No. KJ2019A0453), Returnee Program of Anhui People’s Society Office (Grant No. DT18100035) and Key Project of Scientific Research Fund of Anhui University of Traditional Chinese Medicine (Grant No. 2018zrzd05).

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本校为其他机构

院系归属：

生命科学与环境学院

摘要：

AbstractSalvia miltiorrhiza has numerous compounds with extensive clinical application. “Sweating”, a processing method of Traditional Chinese Medicine (TCM), results in great changes in pharmacology and pharmacodynamics. Previously, chromatogram of 10 characteristic metabolites in S. miltiorrhiza showed a significant difference after “Sweating”. Due to the complexity of TCM, changes in metabolites should be investigated metabolome-wide after “Sweating”. An untargeted UPLC/MS-based metabolomics was performed to discover metabolites profil...

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UPLC/MS-based untargeted metabolomics reveals the changes of metabolites profile of Salvia miltiorrhiza bunge during Sweating processing

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