Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Jiang, Wujiu*;Fan, Shanji;Zhou, Qian;Zhang, Fuxing;Kuang, Daizhi;...

通讯作者：

Jiang, Wujiu;Tan, Yuxing

作者机构：

[Jiang, Wujiu; Jiang, WJ; Tan, Yuxing; Zhang, Fuxing; Kuang, Daizhi] Hengyang Normal Univ, Univ Hunan Prov, Coll Chem & Mat Sci, Key Lab Funct Met Organ Cpds Hunan Prov,Key Lab F, Hengyang 421008, Peoples R China.

[Fan, Shanji] Univ South China, Dept Oncologysurg, Affiliated Hosp 1, Hengyang 421001, Peoples R China.

[Zhou, Qian] Peking Univ, Sch Basic Med Sci, Hlth Sci Ctr, Beijing 100191, Peoples R China.

通讯机构：

[Jiang, WJ; Tan, YX] H

Hengyang Normal Univ, Univ Hunan Prov, Coll Chem & Mat Sci, Key Lab Funct Met Organ Cpds Hunan Prov,Key Lab F, Hengyang 421008, Peoples R China.

语种：

英文

关键词：

Apoptosis;Crystal structure;Organotin complex;Self-assemble;Synthesis

期刊：

Bioorganic Chemistry

ISSN：

0045-2068

年：

2020

卷：

页码：

103402

DOI：

10.1016/j.bioorg.2019.103402

基金类别：

This work was supported by the Science and Technology Development Plan Project of Hengyang City (grant number: 2018KJ121); Hengyang Normal University Industrial Supported Project (grant number: HXKJ201908, HXKJ201911, HXKJ201946, HXKJ201947); and the Foundation of Key Laboratory of Functional Organometallic Materials, University of Hunan Province (grant number: GN19K07).

机构署名：

本校为第一且通讯机构

院系归属：

化学与材料科学学院

摘要：

Eight organotin(IV) complexes (C1-C8) have been synthesized and characterized by elemental analysis, fourier transform infrared spectroscopy (FT-IR), multinuclear nuclear magnetic resonance (1H, 13C and 119Sn NMR), high resolution mass spectroscopy (HRMS) and single crystal X-ray structural analysis. Crystallographic data show that C1 was a tetranuclear 16-membered macrocycle complex, C2-C4 and C7 were centrosymmetric dimer distannoxane and there was a Sn2O2 four-membered ring in the middle of the molecule, respectively, C5 and C6 are monoorgan...

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Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties

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