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A rapidly responding and highly sensitive biosensor for pH-universal detection of ONOO− and its cellular imaging

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成果类型:
期刊论文
作者:
Wang, Feifei;Guo, Beisong;Guo, Xilin;Gu, Biao;Shen, Youming;...
通讯作者:
Gu, B;Shen, YM;Long, JM
作者机构:
[Gu, Biao; Guo, Xilin; Wang, Feifei; Guo, Beisong; Gu, B] Hengyang Normal Univ, Coll Chem & Mat Sci, Key Lab Chem Sensing & Catalysis, Hengyang 421008, Peoples R China.
[Shen, Youming; Shen, YM] Hunan Univ Arts & Sci, Coll Chem & Mat Engn, Changde 415000, Peoples R China.
[Long, Jiumei] Hengyang Normal Univ, Coll Life Sci & Environm, Hengyang 421008, Peoples R China.
通讯机构:
[Long, JM ; Shen, YM ; Gu, B ] H
Hengyang Normal Univ, Coll Chem & Mat Sci, Key Lab Chem Sensing & Catalysis, Hengyang 421008, Peoples R China.
Hunan Univ Arts & Sci, Coll Chem & Mat Engn, Changde 415000, Peoples R China.
Hengyang Normal Univ, Coll Life Sci & Environm, Hengyang 421008, Peoples R China.
语种:
英文
关键词:
Peroxynitrite;Biosensor;ESIPT plus AIE;Rapid response;Cellular imaging
期刊:
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
ISSN:
1010-6030
年:
2022
卷:
427
页码:
113796
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21907026]; Undergrad-uate Innovative Experiment Project of Hengyang Normal University [2]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [20A338]; Scientific Research Fund of Hen-gyang Normal University [2021HSKFJJ021, 19QD18]
机构署名:
本校为第一且通讯机构
院系归属:
化学与材料科学学院
生命科学与环境学院
摘要:
Peroxynitrite (ONOO−) is a highly reactive and short-lived oxidant with low content in cells, and plays an important role in biology. Accordingly, developing a rapid, sensitive, and effective detection approach of cellular ONOO− is very meaningful to further study its biological functions. In this work, a new biosensor BQ for the recognition of ONOO− was facilely synthesized by condensation of 2-hydrazinoquinoline and formylated benzothiazole possessing ‘‘ESIPT + AIE” feature. The probe can be used in a wide range of pH value, and display...

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