作者机构：
[张复兴; 唐文清; 冯泳兰] Department of Chemistry and Materials Science, Key Laboratory of Functional Organometallic Materials, Hengyang Normal University, Hengyang, Hunan 421008, China;College of Resources and Environment, Hunan Agricultural University, Changsha, Hunan 410128, China;[Zeng R.-Y.] Department of Chemistry and Materials Science, Key Laboratory of Functional Organometallic Materials, Hengyang Normal University, Hengyang, Hunan 421008, China, College of Resources and Environment, Hunan Agricultural University, Changsha, Hunan 410128, China
通讯机构：
[Zeng, R.-Y.] D;Department of Chemistry and Materials Science, Key Laboratory of Functional Organometallic Materials, Hengyang Normal University, China
通讯机构：
[Tang, Siping] H;Hengyang Normal Univ, Dept Chem & Mat Sci, Hengyang 421008, Hunan, Peoples R China.
关键词：
DNA binding;Mixed-ligand copper(II) complex;Nuclease activity
摘要：
A mixed-ligand copper(II) complex ((4'-ferrocenyl-2,2':6',2''-terpyridine- k3,N',N'') (1,1'-phenanthroline-k2N,N')-copper(II) bis(perchlorate)) has been synthesized. Binding interactions of the complex with calf thymus DNA (CT-DNA) were investigated by UV-visible and CD spectroscopies. Results show that the copper complex mainly adopt electrostatic attraction binding mode with DNA and the binding constant is (3.22 ± 0.05) × 103 mol-1 L. The complex shows appreciable chemical nuclease activity in the presence of ascorbic acid. The DNA cleavage by the complex were inhibited strongly in the presence of DMSO and tert-butyl alcohol, which suggests that hydroxyl radicals are reactive oxygen species for the cleavage.
摘要：
Bisphenol-A (BPA) is an emerging contaminant with severe toxic effects such as disrupting endocrine system or causing cancer, therefore, developing sensitive and selective sensor for bisphenol-A is very important and interesting. Herein, mesoporous hydroxyapatite (meso- HAP) and mesoporous titanium dioxide (meso-TiO2) have been synthesized and an electrochemical sensor for bisphenol-A was fabricated based on immobilizing meso-hydroxyapatite, meso-TiO2 and multi-walled carbon nanotubes (MWCNT) onto glassy carbon electrode (GCE) surface. Compared with bare electrode and single layer modified electrode, meso-HAP/meso-TiO2/MWCNT modified electrode not only significantly enhanced the oxidation peak current of bisphenol-A, but also lowered the oxidation overpotential, suggesting that the prepared sensor can remarkably improve the determining sensitivity of bisphenol-A. Factors influencing the detection processes were optimized and the kinetic parameters were also investigated. Under the optimized conditions, the oxidation peak current was proportional to bisphenol-A concentration in the range from 8.0 × 10-9-4.0 × 10-7 M with the correlation coefficient of 0.9979. The detection limit was 1.0 × 10-9 M (S/N = 3). The fabricated electrode showed good reproducibility, stability and antiinterference. The proposed method was successfully applied to determine bisphenol-A in plastic products and the results were satisfactory.
作者机构：
[Jiang Wu-Jiu; Feng Yong-Lan; Kuang Dai-Zhi; Zhang Fu-Xing; Wang Jian-Qiu; Yu Jiang-Xi] Hengyang Normal Univ, Dept Chem & Mat Sci, Coll Hunan Prov, Key Lab Funct Organometall Mat, Hengyang 421008, Hunan, Peoples R China.
通讯机构：
[Kuang Dai-Zhi] H;Hengyang Normal Univ, Dept Chem & Mat Sci, Coll Hunan Prov, Key Lab Funct Organometall Mat, Hengyang 421008, Hunan, Peoples R China.
关键词：
organotin carboxylates;synthesis;crystal structure;quantum chemical calculation;thermal stability
摘要：
The tricyclohexyltin nicotinate has been synthesized and characterized by IR, 1H NMR spectra, elemental analysis. The crystal structure has been determined by X-ray diffraction. In the molecular structure of the title complex, the tin atoms are five-coordinated in a distorted trigonal bipyramidal geometry. A one-dimensional linear polymer is formed through an interaction between the N atoms of nicotinic acid and tin atoms of an adjacent tricyclohexyltin nicotinate molecule. Besides, a 3D supramolecular framework is formed by intermolecular C-H··· O bonds. Finally, the stability, frontier orbital composition and energy of the title complex were discussed with Lanl2dz basis set and G03W program. The TG analysis shows that complex is stable below 273 °C. CCDC: 817178.
