Molecularly imprinted fluorescent probe based on FRET for selective and sensitive detection of doxorubicin
作者：
Xu, Zhifeng* ;Deng, Peihong;Li, Junhua;Xu, Li;Tang, Siping
期刊：
Materials Science and Engineering B-Advanced Functional Solid-State Materials ,2017年218:31-39 ISSN：0921-5107
通讯作者：
Xu, Zhifeng
作者机构：
[Tang, Siping; Deng, Peihong; Xu, Zhifeng; Li, Junhua] Hengyang Normal Univ, Key Lab Funct Organometall Mat, Hunan Prov Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;[Xu, Li] South China Agr Univ, Coll Mat & Energy, Dept Appl Chem, Guangzhou 510642, Guangdong, Peoples R China.
通讯机构：
[Xu, Zhifeng] H;Hengyang Normal Univ, Key Lab Funct Organometall Mat, Hunan Prov Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.
关键词：
Doxorubicin;Molecular imprinting;FRET;Molecular recognition;Fluorescent carbon dots
摘要：
In this work, a new type of fluorescent probe for detection of doxorubicin has been constructed by the combined use of fluorescence resonance energy transfer (FRET) technology and molecular imprinting technique (MIT). Using doxorubicin as the template, the molecularly imprinted polymer thin layer was fabricated on the surfaces of carbon dot (CD) modified silica by sol-gel polymerization. The excitation energy of the fluorescent donor (CDs) could be transferred to the fluorescent acceptor (doxorubicin). The FRET based fluorescent probe demonstrated high sensitivity and selectivity for doxorubicin. The detection limit was 13.8 nM. The fluorescent probe was successfully applied for detecting doxorubicin in doxorubicin-spiked plasmas with a recovery of 96.8-103.8%. a relative standard deviation (RSD) of 1.3-2.8%. The strategy for construction of FRET-based molecularly imprinted materials developed in this work is very promising for analytical applications. (C) 2017 Elsevier B.V. All rights reserved.
语种：
英文
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香草醛在四氧化三铁纳米粒子功能化石墨烯修饰电极上的电化学行为及测定
作者：
邓培红;刘晓鹏;贺全国;李俊华
期刊：
衡阳师范学院学报 ,2017年(03):71-77 ISSN：1673-0313
作者机构：
衡阳师范学院 化学与材料科学学院,湖南 衡阳,421008;衡阳师范学院 化学与材料科学学院,湖南 衡阳 421008;湖南工业大学 绿色包装与生物纳米技术应用湖南省重点实验室,湖南 株洲 412007;湖南工业大学 绿色包装与生物纳米技术应用湖南省重点实验室,湖南 株洲,412007;[贺全国] 湖南工业大学
关键词：
化学修饰玻碳电极;四氧化三铁纳米粒子功能化石墨烯;香草醛;测定
摘要：
制备了四氧化三铁纳米粒子功能化石墨烯复合膜修饰玻碳电极,用二阶导数线性扫描伏安法研究香草醛在该修饰电极上的电化学行为,以及支持电解质、富集电位、富集时间、扫描速率等对香草醛伏安响应的影响.实验发现,四氧化三铁纳米粒子功能化石墨烯修饰电极测定香草醛具有较高的灵敏度和选择性.在0.1 mol·L-1 HCl溶液中,香草醛在约936 mV(vs.SCE) 处产生一灵敏的氧化峰.与未修饰的玻碳电极相比,峰电位负移,峰电流显著增加,说明该修饰电极对香草醛的电化学响应具有很好的催化增敏作用.利用二阶导数线性扫描伏安法进行定量分析,峰电流与香草醛的浓度在1.0×10-7 mol·L-1~1.0×10-5 mol·L-1和1.0×10-5 mol·L-1~1.0×10-4 mol·L-1范围内呈良好的线性关系,检出限为6.0×10-8 mol·L-1.
语种：
中文
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一种用于检测三氯生的电化学传感器及其制备方法和应用
发明/设计人：
李俊华;刘梦琴;许志锋;张复兴;贺娇;...
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201710567293.5
申请时间：
2017-7-12
公开号：
CN107328836A
公开时间：
2017-11-07
主申请人地址：
421000 湖南省衡阳市雁峰区黄白路165号
摘要：
本发明涉及电化学检测技术领域，具体公开了一种用于检测三氯生的电化学传感器及其制备方法和应用。所述的电化学传感器以用于检测三氯生的化学修饰电极为工作电极、Ag‑AgCl为参比电极和铂电极为辅助电极构成三电极体系，将三电极体系组装后与电化学工作站相连构成电化学传感器。所述的用于三氯生定量检测的化学修饰电极以及电化学传感器，该电极或传感器对三氯生具有优异的电催化活性；以及具有极低的检出限、良好的稳定性、抗干扰性和重现性。
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Designed synthesis of LaCoO3/N-doped reduced graphene oxide nanohybrid as an efficient bifunctional electrocatalyst for ORR and OER in alkaline medium
作者：
Liu, Kun;Li, Jun;Wang, Qunfeng;Wang, Xipeng;Qian, Dong* ;...
期刊：
Journal of Alloys and Compounds ,2017年725:260-269 ISSN：0925-8388
通讯作者：
Qian, Dong;Li, Junhua;Chen, Zehua
作者机构：
[Li, Jun; Liu, Kun; Wang, Qunfeng; Wang, Xipeng; Jiang, Jianbo; Qian, Dong] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.;[Li, Junhua] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;[Chen, Zehua] Henan Polytech Univ, Sch Mat Sci & Engn, Jiaozuo 454000, Peoples R China.;[Jiang, Jianbo] Jishou Univ, Coll Chem & Chem Engn, Jishou 416000, Peoples R China.
通讯机构：
[Qian, Dong] C;[Li, Junhua; Chen, Zehua] H;Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.;Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;Henan Polytech Univ, Sch Mat Sci & Engn, Jiaozuo 454000, Peoples R China.
关键词：
LaCoO3/N-rGO;Preparation;Oxygen reduction reaction;Oxygen evolution reaction;Bifunctional electrocatalyst
摘要：
Developing inexpensive and advanced bifunctional electrocatalysts as substitutes for commercial precious metal-based electrocatalysts for oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is of tremendous expectancy for rechargeable metal-air batteries. Herein, we demonstrate a rational wet-chemical route to fabricate a novel LaCoO3/N-doped reduced graphene oxide (LaCoO3/N-rGO) nanohybrid with improved performances as a bifunctional electrocatalyst for ORR and OER. The as-synthesized LaCoO3/N-rGO affords overwhelmingly superior ORR and OER electrocatalytic properties in comparison with LaCoO3, N-rGO and LaCoO3/reduced graphene oxide (LaCoO3/rGO). As compared with the most acknowledgedly efficient Pt-based bifunctional eletrocatalysts, e.g. 20 wt% Pt/C, LaCoO3/N-rGO displays a far higher OER activity associated with remarkably enhanced ORR and OER durabilities. Moreover, LaCoO3/N-rGO holds a better durability and a more rapid OER rate than those of the benchmark OER electrocatalyst RuO2. The improved ORR and OER electrocatalytic performances for LaCoO3/N-rGO stem from the diminished size of LaCoO3 on rGO, reinforced synergistic effect between LaCoO3 and rGO, efficient N doping, and significantly low ohmic and kinetic impedances. This design strategy can be extended to construct composites of other perovskite-type oxides and carbonaceous materials, thereby providing the foundation for the developments of bifunctional eletrocatalysts in the rechargeable metal−air batteries.
语种：
英文
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一种快速检测过氧化氢的无酶电化学传感器及其制备方法和应用
发明/设计人：
李俊华;许志锋;刘梦琴;张复兴;郭芬;...
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201710547494.9
申请时间：
2017-7-6
公开号：
CN107356643A
公开时间：
2017-11-17
主申请人地址：
421000 湖南省衡阳市雁峰区黄白路165号
摘要：
本发明涉及电化学检测技术领域，具体公开了一种快速检测过氧化氢的无酶电化学传感器及其制备方法和应用。所述快速检测过氧化氢的无酶电化学传感器的工作电极选用无酶化学修饰电极。所述的无酶化学修饰电极的制备方法，包含如下步骤：(1)制备N‑RGO；(2)制备Ag@Cu<sub>2</sub>O/N‑RGO：(3)将步骤(2)制备得到的Ag@Cu<sub>2</sub>O/N‑RGO修饰在玻碳电极上即得所述的快速检测过氧化氢的无酶化学修饰电极。由本发明无酶化学修饰电极组成的无酶电化学传感器能实现过氧化氢的现场快速检测，具有携带便利、操作简单、成本低廉、灵敏度高和检出限低等优点，在环境保护、食品安全和临床医疗等方面有着广泛的应用前景。
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一种三(邻溴苄基)锡水杨酸酯配合物及其制备方法与应用
发明/设计人：
张复兴;朱小明;邝代治;冯泳兰;庾江喜;...
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201710842058.4
申请时间：
2017-9-18
公开号：
CN107602606A
公开时间：
2018-1-19
主申请人地址：
421008 湖南省衡阳市雁峰区黄白路165号
摘要：
本发明公开的一种三(邻溴苄基)锡水杨酸酯配合物及其制备方法与应用，为如下结构式(I)的配合物。本发明还公开了三(邻溴苄基)锡水杨酸酯配合物制备方法和在制备治疗癌症药物中的应用。<img file="DDA0001410998910000011.TIF" wi="368" he="391" />
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Benzo[1,2-b;4,5-bʹ]dithiophene-bridged bimetal complexes with different redox-active terminals: Syntheses, characterization and charge delocalization studied by spectro-electrochemical and DFT methods
作者：
Ou, Ya-Ping* ;Hu, Fang;Tang, Shunlin;Yu, Jiangxi;Li, Junhua;...
期刊：
Journal of Organometallic Chemistry ,2017年843:66-74 ISSN：0022-328X
通讯作者：
Ou, Ya-Ping
作者机构：
[Ou, Ya-Ping; Tang, Shunlin; Yu, Jiangxi; Li, Junhua; Zhang, Fuxing; Kuang, Daizhi] Hengyang Normal Univ, Coll Hunan Prov, Coll Chem & Mat Sci, Key Lab Funct Organometall Mat, Hengyang 421008, Hunan, Peoples R China.;[Hu, Fang] Ningbo Univ, Fac Mat Sci & Chem Engn, Ningbo 315211, Zhejiang, Peoples R China.
通讯机构：
[Ou, Ya-Ping] H;Hengyang Normal Univ, Coll Hunan Prov, Coll Chem & Mat Sci, Key Lab Funct Organometall Mat, Hengyang 421008, Hunan, Peoples R China.
关键词：
Benzo[1,2-b;4,5-b ']dithiophene;Electrochemistry;Spectroelcetrochemistry;Redox characteristics
摘要：
Benzo[1,2-b;4,5-bʹ]dithiophene have been used as bridge ligand to build up binuclear iron ethynylene complex 1 and ruthenuim vinylene complex 2, and their electronic and optical properties were investigated by electrochemistry, IR and UV–vis–NIR spectroelectrochemistry and theoretical calculations. These properties of two complexes 1 and 2, for comparison, of the previously reported ruthenium ethynylene complex 3 was analyzed. Complexes 1–3 exhibit obvious different redox characteristics. The highest anodic potentials and the largest ΔE value were found in ruthenium vinylene complex 2. IR spectroelcetrochemistry results show that two intense ν(C≡C) bands of monocation 1<sup>+</sup>feature more larger ν(C≡C) separation (73 cm<sup>−1</sup>) than that of 3<sup>+</sup>(36 cm<sup>−1</sup>), and ν(C≡O) band in 2 exhibit little changes upon electrolytic experiments. The NIR broad absorptions of different strength and energy were found in singly-oxidized 1<sup>+</sup>-3<sup>+</sup>, which may be assigned to MLCT and proved further by DFT-TDDFT calculations. Similar to 3<sup>+</sup>, different conformations from the relative position difference between metal terminal groups and bridge ligands may be attributable to broad NIR absorptions of 1<sup>+</sup>. ©2017 Elsevier B.V.
语种：
英文
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Facile synthesis of MnO2-embedded flower-like hierarchical porous carbon microspheres as an enhanced electrocatalyst for sensitive detection of caffeic acid
作者：
Li, Junhua;Jiang, Jianbo;Liu, Mengqin;Xu, Zhifeng;Deng, Peihong;...
期刊：
Analytica Chimica Acta ,2017年985:155-165 ISSN：0003-2670
通讯作者：
Qian, Dong;Yang, Chunming
作者机构：
[Liu, Mengqin; Deng, Peihong; Xu, Zhifeng; Li, Junhua; Tong, Chaoying] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;[Li, Junhua; Jiang, Jianbo; Qian, Dong] Cent S Univ, Hunan Prov Key Lab Efficient & Clean Utilizat Man, Changsha 410083, Hunan, Peoples R China.;[Xie, Haobin; Li, Junhua] Hengyang Normal Univ, Key Lab Funct Organometall Mat, Hengyang 421008, Peoples R China.;[Qian, Dong] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China.;[Yang, Chunming] Hunan Normal Univ, Coll Chem & Chem Engn, Changsha 410081, Hunan, Peoples R China.
通讯机构：
[Qian, Dong] C;[Yang, Chunming] H;Cent S Univ, Hunan Prov Key Lab Efficient & Clean Utilizat Man, Changsha 410083, Hunan, Peoples R China.;Hunan Normal Univ, Coll Chem & Chem Engn, Changsha 410081, Hunan, Peoples R China.
关键词：
Caffeic acid;Carbon microspheres;Electrochemical sensor;MnO(2) nanorods
摘要：
Tailored designs/fabrications of hierarchical porous advanced electrode materials are of great importance for developing high-performance electrochemical sensors. Herein, we demonstrate a simple and low-cost in situ chemical approach for the facile synthesis of MnO<inf>2</inf>-embedded hierarchical porous carbon microspheres (MnO<inf>2</inf>/CM). By the characterizations of scanning electron microscopy, X-ray photoelectron spectroscopy, X-ray powder diffraction and energy dispersive spectroscopy, we evidenced that the synthesized product were flower-like carbon microspheres (CM) assembled by the bent flakes with thickness of about several nanometers and MnO<inf>2</inf>nanorods were highly dispersed and successfully decorated on the CM layers, resulting in a rough surface and three-dimensional microstructure. The greatest benefit from the combined porous CM with MnO<inf>2</inf>nanorods is that the MnO<inf>2</inf>/CM modified electrode has the synergetic catalysis effect on the electro-oxidation of caffeic acid, leading to the remarkable increase in the electron transfer rate and significant decrease in the over-potential for the caffeic acid oxidation in contrast to the bare electrode and CM modified electrode. This implies that the prepared MnO<inf>2</inf>/CM can be employed as an enhanced electrocatalyst for the sensitive detection of caffeic acid. Under the optimum conditions, the anodic peak current of caffeic acid is linear with its concentration in the range of 0.01–15.00 μmol L<sup>−1</sup>, and a detection limit of 2.7 nmol L<sup>−1</sup>is achieved based on S/N = 3. The developed sensor shows good selectivity, sensitivity, reproducibility, and also excellent recovery in the detections of real samples, revealing the promising practicality of the sensor for the caffeic acid detection.<br/> ©2017 Elsevier B.V.
语种：
英文
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A highly efficient visible-light-responding Cu2 O−TiO2 /g-C3 N4 photocatalyst for instantaneous discolorations of organic dyes
作者：
Min, Ziyan;Wang, Xipeng;Li, Yaping;Jiang, Jianbo;Li, Jun;...
期刊：
Materials Letters ,2017年193(Apr.15):18-21 ISSN：0167-577X
通讯作者：
Qian, Dong;Li, Junhua
作者机构：
[Li, Jun; Wang, Xipeng; Jiang, Jianbo; Qian, Dong; Min, Ziyan; Li, Yaping] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.;[Li, Junhua] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.
通讯机构：
[Qian, Dong] C;[Li, Junhua] H;Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China.;Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.
关键词：
Cu2OTiO2/g-C3N4;Nanocomposites;Semiconductors;Photocatalyst;Discoloration;Organic dyes
摘要：
We designed and synthesized a novel Cu2OTiO2/g-C3N4 ternary heterostructure nanohybrid, which is a universal and specific visible-light-responding photocatalyst for instantaneous discolorations of organic dyes. Employing this said nanohybrid, rhodamine B, methylene blue and methyl orange can be fully discolored within 3, 10 and 15 min in the presence of H2O2 under visible-light irradiation, respectively. (C) 2017 Elsevier B.V. All rights reserved.
语种：
英文
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一种用于检测酪氨酸的电化学传感器及其制备方法和应用
发明/设计人：
李俊华,刘梦琴,许志锋,张复兴,耿弘吏,贺灵芝
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201710567292.0
申请时间：
2017-7-12
公开号：
CN107153088A
公开时间：
2017-9-12
主申请人地址：
421000 湖南省衡阳市雁峰区黄白路165号
摘要：
本发明涉及电化学检测技术领域，具体涉及一种用于检测酪氨酸的电化学传感器及其制备方法和应用。所述的电化学传感器，以用于检测酪氨酸的化学修饰电极为工作电极，Ag‑AgCl为参比电极，铂丝电极为辅助电极，利用三电极法组装电极测试体系后连接电化学工作站得用于检测酪氨酸的电化学传感器。所述的用于酪氨酸定量检测的化学修饰电极或电化学传感器具有极低的检出限和较宽的检测范围以及良好的稳定性、抗干扰性和重现性。
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一种用于沙丁胺醇定量检测的分子印迹型电化学传感器及其制备方法
发明/设计人：
李俊华;许志锋;刘梦琴;邓培红;唐斯萍;...
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201610705752.7
申请时间：
2016-8-23
公开号：
CN106290518A
公开时间：
2017-01-04
主申请人地址：
421008 湖南省衡阳市雁峰区黄白路165号
摘要：
本发明涉及电分析化学技术领域，具体公开了一种用于沙丁胺醇定量检测的分子印迹型电化学传感器及其制备方法。所述制备方法，包含如下步骤：S1～S4.制备N??RGO；S5.取N??RGO在水中超声分散，然后加入葡萄糖形成溶液A；S6.将NH<sub>3</sub>·H<sub>2</sub>O溶液加入到硝酸银溶液中，形成溶液B；S7.将溶液B和溶液A混合，搅拌，然后陈化，经离心、洗涤、干燥得Ag??N??RGO纳米复合材料；S8.取Ag??N??RGO纳米复合材料分散于有机溶剂中，然后涂覆在工作电极的表面，得Ag??N??RGO修饰电极；S9.将Ag??N??RGO修饰电极置于含邻苯二胺和沙丁胺醇的PBS缓冲溶液中进行循环伏安法扫描；S10.将经步骤S9处理过的电极除去聚合膜中的沙丁胺醇，得到MIP/Ag??N??RGO印迹电极。所述的化学电极或化学传感器具有极低的检出限以及良好的稳定性、抗干扰性和重现性。
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一种锡氧杂环结构的二丁基锡2,4,5?三氟?3?甲氧基?苯甲酸酯配合物及其制备方法与应用
发明/设计人：
朱小明;庾江喜;蒋伍玖;张复兴;冯泳兰;...
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201610684686.X
申请时间：
2016-8-18
公开号：
CN106279257A
公开时间：
2017-01-04
主申请人地址：
421002 湖南省衡阳市珠晖区衡花路16号
摘要：
本发明公开的一种锡氧杂环结构的二丁基锡2,4,5??三氟??3??甲氧基??苯甲酸酯，为如下结构式(I)的配合物<img file="483293dest_path_image001.TIF" wi="376" he="176" />式中R表示正丁基。本发明还公开了该锡氧杂环结构的二丁基锡2,4,5??三氟??3??甲氧基??苯甲酸酯配合物的制备方法和在制备抗肿瘤药物中的应用。
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产学研结合模式下分析化学实验教学改革探索
作者：
邓培红;李俊华;曾荣英;唐斯萍
期刊：
衡阳师范学院学报 ,2016年37(03):152-155 ISSN：1673-0313
作者机构：
衡阳师范学院 化学与材料科学学院,湖南 衡阳,421008;[邓培红; 曾荣英; 唐斯萍; 李俊华] 衡阳师范学院
关键词：
产学研结合;分析化学;实验教学;就业能力
摘要：
“产学研结合”是高等学校教育实现人才培养目标的重要途径之一。该文针对传统分析化学实验教学存在的问题，在“产学研”人才培养模式下结合应用化学专业特色对分析化学实验的教学内容、教学方法、考核形式等方面进行探索与实践，提高教学质量，培养学生的科研创新能力，更好地实现应用型人才的培养目标。
语种：
中文
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Facile synthesis of 3D porous nitrogen-doped graphene as an efficient electrocatalyst for adenine sensing
作者：
Li, Junhua;Jiang, Jianbo;Feng, Haibo;Xu, Zhifeng;Tang, Siping;...
期刊：
RSC Advances ,2016年6(37):31565-31573 ISSN：2046-2069
通讯作者：
Qian, Dong
作者机构：
[Feng, Haibo; Li, Junhua; Jiang, Jianbo; Qian, Dong] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China.;[Tang, Siping; Deng, Peihong; Xu, Zhifeng; Li, Junhua] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;[Li, Junhua; Qian, Dong] Cent S Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China.
通讯机构：
[Qian, Dong] C;Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China.;Cent S Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China.
摘要：
In this work, a simple, low-cost and eco-friendly strategy for fabricating the three-dimensional porous nitrogen-doped graphene (3D-N-GN) is demonstrated by combining the hydrothermal assembly and freeze-drying process without using any framework support. The desired features for 3D-N-GN, such as rich macroporosity, nitrogen-doping structure and high active surface area have been confirmed by scanning electron microscopy, X-ray photoelectron spectroscopy and electrochemical techniques, respectively. In comparison with two-dimensional graphene (2D-GN) and nitrogen-doped graphene (2D-N-GN), 3D-N-GN makes a more negative shift in the oxidation peak potential of adenine together with a remarkable increase in the oxidation peak current, highlighting the importance of the nitrogen-doping and 3D construction of the graphene-based support for improving the electrocatalytic performance. It also indicates that 3D-N-GN can be used as an efficient electrocatalyst for adenine sensing. Furthermore, the sensing conditions are optimized and the resulting sensor displays excellent analytical performance in the detection of adenine at low concentrations ranging from 0.02 to 1.20 μM, with a detection limit of 8 nM. Finally, this proposed method not only exhibits preferable reproducibility, stability and adequate sensitivity, but also demonstrates good efficiency in the detection of adenine in biological fluids. ©The Royal Society of Chemistry 2016.
语种：
英文
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一种梯形结构的有机锡水杨酸酯配位聚合物及其制备方法与应用
发明/设计人：
张复兴;邝代治;冯泳兰;朱小明;庾江喜;...
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201610182016.8
申请时间：
2016-3-28
公开号：
CN105884817A
公开时间：
2016-08-24
主申请人地址：
421008 湖南省衡阳市雁峰区黄白路165号
摘要：
本发明公开的一种梯形结构的有机锡聚合物μ<sub>2</sub>‑O、μ<sub>3</sub>‑O桥联二(p‑氯苄基)锡水杨酸酯配位聚合物，为如下结构式(1)的合物。本发明还公开了梯形结构的有机锡聚合物μ<sub>2</sub>‑O、μ<sub>3</sub>‑O桥联的二(p‑氯苄基)锡水杨酸酯配位聚合物制备方法及在制备抗肿瘤药物中的应用。<img file="DDA0000951722670000011.TIF" wi="1021" he="758" />
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Fluorescent molecularly imprinted polymers based on 1,8-naphthalimide derivatives for efficiently recognition of cholic acid
作者：
Xu, Zhifeng* ;Deng, Peihong;Tang, Siping;Li, Junhua
期刊：
Materials Science and Engineering C: Materials for Biological Applications ,2016年58:558-567 ISSN：0928-4931
通讯作者：
Xu, Zhifeng
作者机构：
[Tang, Siping; Deng, Peihong; Xu, Zhifeng; Li, Junhua] Hengyang Normal Univ, Coll Chem & Mat Sci, Key Lab Funct Organometall Mat Hunan Prov Univ, Hengyang 421008, Peoples R China.;[Xu, Zhifeng] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.
通讯机构：
[Xu, Zhifeng] H;Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.
关键词：
1,8-naphthalimide;Cholic acid;Fluorescence intensity;Molecular imprinting;Molecular recognition
摘要：
Fluorescent molecularly imprinted polymers (MIPs) have attracted increasing attentions in recent years due to their high selectivity and sensitivity for target molecules. In this study, two cholic acid imprinted fluorescent polymers, i.e., MIP<inf>1</inf>and MIP<inf>2</inf>, were prepared using 4-dimethylamino-N-allylnaphthalimide (F<inf>1</inf>) and 4-piperazinyl-N-allylnaphthalimide (F<inf>2</inf>) as the fluorescent functional monomers, respectively. The fluorescence intensity of MIP<inf>1</inf>decreased linearly with the increase of the template concentration in the range of 1.50-120.0 μM, while the fluorescence intensity of MIP<inf>2</inf>increased linearly with the increase of the template concentration in the range of 0.40-110.0 μM. The detection limits of MIP<inf>1</inf>and MIP<inf>2</inf>for cholic acid were 0.42 and 0.083 μM, respectively. The mechanisms of the fluorescence responsive of the imprinted polymers were discussed. The results of fluorescence measurement and binding experiments demonstrated that both imprinted polymers have high recognition abilities and binding affinities for the template. The imprinted polymers have been successfully applied to the determination of cholic acid in human serums. The present study indicated that 1,8-naphthalimide can be used as a modular building block for design and construction of various fluorogenic molecularly imprinted materials for practical sensing and separation. ©2015 Elsevier B.V. All rights reserved.
语种：
英文
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理想完全互溶双液系相图的数学解析
作者：
刘兴;屈景年;周立君;赖华;曾荣英;...
期刊：
大学化学 ,2016年31(7):96-100 ISSN：1000-8438
作者机构：
衡阳师范学院化学与材料科学学院,湖南衡阳,421008;衡阳师范学院数学与统计学院,湖南衡阳,421001
关键词：
理想完全互溶双液系;相图;函数解析式;Clausius-Clapeyron方程
摘要：
理想完全互溶双液系是两个组分都严格遵守Raoult 定律的体系，从数学角度看，其平面相图有着确定的函数关系。本文以Clausius-Clapeyron 方程为基础，推导了该类理想体系的p-x、T-x 及p-T相图的函数解析式。
语种：
中文
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一种用于左旋多巴胺定量检测的电化学传感器及其制备方法
发明/设计人：
李俊华;刘梦琴;张复兴;许志锋;邓培红;...
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201610475506.7
申请时间：
2016-6-27
公开号：
CN106198665A
公开时间：
2016-12-7
主申请人地址：
421008 湖南省衡阳市雁峰区黄白路165号
摘要：
本发明涉及电分析化学技术领域，具体公开了一种用于左旋多巴胺定量检测的电化学传感器及其制备方法。所述的用于左旋多巴胺定量检测的化学电极的制备方法，其特征在于，包含如下步骤：S1.将柠檬酸和氧化石墨烯分散在水中，形成溶液1；S2.将FeCl<sub>3</sub>和NiCl<sub>2</sub>·6H<sub>2</sub>O溶解在水中，形成溶液2；S3.将溶液2逐滴加入到溶液1中，调节pH值为9~10后搅拌1~2h形成混合悬浊液；S4.在上述悬浊液中加入肼继续搅拌1~2h，然后陈化10~12h，经离心、洗涤、干燥得NiFe<sub>2</sub>O<sub>4</sub>/RGO纳米复合材料；S5.将NiFe<sub>2</sub>O<sub>4</sub>/RGO纳米复合材料超声分散后，涂覆在工作电极的表面，得NiFe<sub>2</sub>O<sub>4</sub>/RGO复合膜修饰电极。所述的电极或由所述电极制备得到的化学传感器在左旋多巴胺的检测过程中具有极低的检出限以及良好的稳定性、抗干扰性以及重现性。
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三苯基锡对羟基苯甲酸酯配合物及其制备方法与应用
发明/设计人：
朱小明;张复兴;邝代治;冯泳兰;庾江喜;...
申请/专利权人：
衡阳师范学院
申请/专利号：
CN201610182810.2
申请时间：
2016-3-28
公开号：
CN105837619A
公开时间：
2016-8-10
主申请人地址：
421008 湖南省衡阳市雁峰区黄白路165号
摘要：
本发明公开的三苯基锡对羟基苯甲酸酯配合物及其制备方法与应用，为如下结构式(1)的化合物。本发明还公开了三苯基锡对羟基苯甲酸酯配合物的制备方法及在制备抗肿瘤药物中的应用。<img file="DDA0000951721270000011.TIF" wi="938" he="398" />
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数学函数在物理化学相平衡教学中的应用
作者：
刘兴;赖华;周立君;屈景年;李俊华
期刊：
化学教育(中英文) ,2016年37(20):24-26 ISSN：1003-3807
作者机构：
衡阳师范学院化学与材料科学学院 湖南衡阳421008;衡阳师范学院数学与统计学院 湖南衡阳421001
关键词：
物理化学;相图;数学函数;理想完全互溶双液系;理想固溶体体系
摘要：
理想完全互溶双液系、理想完全互溶固溶体相图是其他双组分相图的基础。以理想溶液热力学理论为基础，分别对这2类相图进行了函数解析并给出了理论上的相图，其与已知的标准相图一致，对学习和研究相平衡有一定指导与参考意义。
语种：
中文
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