期刊：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2026年346:126921 ISSN：1386-1425
通讯作者：
Li, Zhongliang;Chen, Wen
作者机构：
[Liu, Mengqin; Chen, Taiyi; Lin, Xiaoping; Zeng, Rongying; Jiang, Lu; Li, Peisong; Huang, Leyuan] Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metal Pollution in the Upper Reaches of Xiangjiang River, College of Chemistry and Material Science, Hengyang Normal University, Hengyang 421001, PR China;[Liu, Wei] Hunan Hengyang Ecological Environment Monitoring Center, Hengyang, Hunan 421001, China;[Li, Zhongliang] Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metal Pollution in the Upper Reaches of Xiangjiang River, College of Chemistry and Material Science, Hengyang Normal University, Hengyang 421001, PR China. Electronic address: zhongliang.li@hynu.edu.cn;[Zhu, Ruirui] Hunan Provincial Ecological and Environmental Monitoring Center, State Environmental Protection Key Laboratory of Monitoring for Heavy Metal Pollution, Changsha 410019, China;[Chen, Zhi-Liang] School of Pharmacy, Shaoyang University, Shaoyang 422000, PR China
通讯机构：
[Chen, Wen; Li, Zhongliang] H;Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metal Pollution in the Upper Reaches of Xiangjiang River, College of Chemistry and Material Science, Hengyang Normal University, Hengyang 421001, PR China. Electronic address:
关键词：
AIE;J-aggregate;Ratiometric fluorescence sensors;Zinc and copper ions
摘要：
The precise detection of metal ions is crucial in food safety, biomedical diagnostics, and environmental monitoring. Although traditional “on-off” fluorescence probes are frequently utilized, their anti-interference capability remains a limitation. This study synthesized three new copper-based fluorescent probes: PTA, PTP, and PTD. Among them, PTD exhibited unique aggregation-induced emission (AIE) properties. PTD's remarkable selectivity for Zn 2+ was due to the formation of Zn 2+ -induced J-aggregates, which resulted in a concentration-dependent fluorescence redshift from green to yellow and then to red. Additionally, PTD demonstrated a rapid and sensitive response to Cu 2+ , and it was successfully integrated into a smartphone-based platform for the semi-quantitative detection of Zn 2+ and Cu 2+ in real food samples. The effectiveness in biological applications was also validated through live-cell imaging tests. This work contributes to the creation of highly selective and interference-resistant ratiometric fluorescence sensors by leveraging the special process of target metal ion-induced J-aggregate production in AIE-based probes.
The precise detection of metal ions is crucial in food safety, biomedical diagnostics, and environmental monitoring. Although traditional “on-off” fluorescence probes are frequently utilized, their anti-interference capability remains a limitation. This study synthesized three new copper-based fluorescent probes: PTA, PTP, and PTD. Among them, PTD exhibited unique aggregation-induced emission (AIE) properties. PTD's remarkable selectivity for Zn 2+ was due to the formation of Zn 2+ -induced J-aggregates, which resulted in a concentration-dependent fluorescence redshift from green to yellow and then to red. Additionally, PTD demonstrated a rapid and sensitive response to Cu 2+ , and it was successfully integrated into a smartphone-based platform for the semi-quantitative detection of Zn 2+ and Cu 2+ in real food samples. The effectiveness in biological applications was also validated through live-cell imaging tests. This work contributes to the creation of highly selective and interference-resistant ratiometric fluorescence sensors by leveraging the special process of target metal ion-induced J-aggregate production in AIE-based probes.
期刊：
Journal of the Taiwan Institute of Chemical Engineers,2026年180:106480 ISSN：1876-1070
通讯作者：
Wenjin Ni
作者机构：
[Shuilin Liu; Ning Liu; Xinde Tang; Suyun Wu; Aiming Sun; Aiyang Li] School of chemical and environmental engineering, Hunan Institute of Technology, Hengyang 421002, China;College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, China;Key Laboratory of Functional Metal-Organic Compounds of Hunan Province, Hengyang 421008, China;[Wenjin Ni] College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, China<&wdkj&>Key Laboratory of Functional Metal-Organic Compounds of Hunan Province, Hengyang 421008, China
通讯机构：
[Wenjin Ni] C;College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, China<&wdkj&>Key Laboratory of Functional Metal-Organic Compounds of Hunan Province, Hengyang 421008, China
摘要：
Background The growing demand for ε-caprolactam, a key precursor for nylon-6 production, has driven strategic interest in developing cost-effective and environmentally benign approaches for cyclohexanone oxime synthesis.
The growing demand for ε-caprolactam, a key precursor for nylon-6 production, has driven strategic interest in developing cost-effective and environmentally benign approaches for cyclohexanone oxime synthesis.
Methods Ti-incorporated hexagonal mesoporous silica (TiO 2 /Ti-HMS) catalysts with tunable Ti/Si molar ratios were in-situ synthesized, and applied in the selective aerobic oxidation of cyclohexylamine to cyclohexanone oxime. The textural properties of TiO 2 /Ti-HMS were characterized, and the bifunctional effects of surface hydroxyls sites and Brønsted acid centers were investigated. The adsorption energies of both cyclohexylamine and nitrosocyclohexane intermediate on different catalysts were calculated by density functional theory (DFT).
Ti-incorporated hexagonal mesoporous silica (TiO 2 /Ti-HMS) catalysts with tunable Ti/Si molar ratios were in-situ synthesized, and applied in the selective aerobic oxidation of cyclohexylamine to cyclohexanone oxime. The textural properties of TiO 2 /Ti-HMS were characterized, and the bifunctional effects of surface hydroxyls sites and Brønsted acid centers were investigated. The adsorption energies of both cyclohexylamine and nitrosocyclohexane intermediate on different catalysts were calculated by density functional theory (DFT).
Significant Findings The incorporation of partial titanium species into the HMS framework via Ti-O-Si bonds, while the remaining titanium formed highly dispersed TiO 2 nanoparticles to form the TiO 2 /Ti-HMS catalyst. The surface hydroxyls on anatase TiO 2 nanoparticles promoted the adsorption and activation of cyclohexylamine. Meanwhile, the skeletal titanium in the HMS framework enriched the Brønsted acid centers, which promoted the rearrangement of the nitrosocyclohexane intermediate to cyclohexanone oxime. Bifunctional Ti-HMS-0.05 exhibited superior catalytic performance and stability. A possible reaction pathway was proposed based on the experimental results and DFT calculations.
The incorporation of partial titanium species into the HMS framework via Ti-O-Si bonds, while the remaining titanium formed highly dispersed TiO 2 nanoparticles to form the TiO 2 /Ti-HMS catalyst. The surface hydroxyls on anatase TiO 2 nanoparticles promoted the adsorption and activation of cyclohexylamine. Meanwhile, the skeletal titanium in the HMS framework enriched the Brønsted acid centers, which promoted the rearrangement of the nitrosocyclohexane intermediate to cyclohexanone oxime. Bifunctional Ti-HMS-0.05 exhibited superior catalytic performance and stability. A possible reaction pathway was proposed based on the experimental results and DFT calculations.
作者机构：
State Key Laboratory of Silicate Materials for Architectures, Wuhan University of Technology, Wuhan 430070, China;[Quanyao Zhu] School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070 Hubei, China;Advanced Ceramics Institute of Zibo New & High-Tech Industrial Development Zone, Zibo 255000 Shandong, China;College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421002, China;[Jianing Zhu; Jia He; Piyu Gong; Fuling Wu; Wenqi Sun; Zijin Meng; Qingqing Zhang; Dongchun Qiu; Huajun Sun] State Key Laboratory of Silicate Materials for Architectures, Wuhan University of Technology, Wuhan 430070, China<&wdkj&>School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070 Hubei, China<&wdkj&>Advanced Ceramics Institute of Zibo New & High-Tech Industrial Development Zone, Zibo 255000 Shandong, China
通讯机构：
[Quanyao Zhu] S;School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070 Hubei, China
摘要：
This paper demonstrates a heterostructured capacitor combining low-hysteresis Pb 0.94 La 0.06 ZrO 3 (PLZ) with high-polarization Pb 0.94 La 0.06 (Zr 0.52 Ti 0.48 )O 3 (PLZT) on LaNiO3/Si substrates. Strategic insertion of Al 2 O 3 (AO) interlayer at PLZT/PLZ interface effectively suppressed leakage currents while optimizing electric field distribution, substantially enhancing breakdown field strength from 2057 kV/cm to 3620 kV/cm. Optimized PLZT/AO/PLZ heterostructure exhibited outstanding energy storage performance, achieving record-high recoverable energy density of 101.4 J/cm 3 with 74.7 % energy conversion efficiency, providing a breakthrough solution for lead zirconate titanate-based thin film energy storage devices.
This paper demonstrates a heterostructured capacitor combining low-hysteresis Pb 0.94 La 0.06 ZrO 3 (PLZ) with high-polarization Pb 0.94 La 0.06 (Zr 0.52 Ti 0.48 )O 3 (PLZT) on LaNiO3/Si substrates. Strategic insertion of Al 2 O 3 (AO) interlayer at PLZT/PLZ interface effectively suppressed leakage currents while optimizing electric field distribution, substantially enhancing breakdown field strength from 2057 kV/cm to 3620 kV/cm. Optimized PLZT/AO/PLZ heterostructure exhibited outstanding energy storage performance, achieving record-high recoverable energy density of 101.4 J/cm 3 with 74.7 % energy conversion efficiency, providing a breakthrough solution for lead zirconate titanate-based thin film energy storage devices.
期刊：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,2026年346:126928 ISSN：1386-1425
通讯作者：
Dai, Cong;Xu, Zhifeng
作者机构：
[Xu, Ying] College of Chemistry and Materials Science, Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River, Hengyang Normal University, Hengyang 421001, China;[Dai, Cong] College of Chemistry and Materials Science, Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River, Hengyang Normal University, Hengyang 421001, China. Electronic address: daicong@hynu.edu.cn;[Xu, Zhifeng] College of Chemistry and Materials Science, Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River, Hengyang Normal University, Hengyang 421001, China. Electronic address: 1760321030@qq.com
通讯机构：
[Dai, Cong; Xu, Zhifeng] C;College of Chemistry and Materials Science, Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River, Hengyang Normal University, Hengyang 421001, China. Electronic address:
关键词：
Dual-channel sensing;Hypochlorous acid;Organic cage;Ratiometric signal
摘要：
The high-performance detection of hypochlorous acid (HClO) is crucial for life and environmental health, but still challenging for the single fluorescence signal and single sensing channel of probes. Organic cage with strong adsorption ability and cage structure-related fluorescence property, is a type of potential fluorescent probe. However, the single signal and short emission of organic cage hinders its sensing performance. The design of dual emitting organic cage with long wavelength for dual-channel ratiometric sensing of HClO is of great significance. Herein, we reported an organic cage (ROX) as a probe for accurate quantification of HClO. The prepared ROX exhibited capsule topology-facilitated red/green dual emission around 660/502 nm. The cage-like structure was disrupted by the rapid specific redox interaction between imine bond in ROX and HClO. As a result, the fluorescence at 660 nm quenched in conjunction with the enhancement at 502 nm in PBS (pH 4). Besides, the fluorescence increased at 582 nm with constant emission at 480 nm in DMSO/PBS (pH 7) ( V / V , 9/1). The ratio signal in PBS and DMSO/PBS respectively gave the linearity range of 1–30 and 20–45 μM, the limit of detection (3 s ) of 14 and 49 nM, and the relative standard deviation of 1.04 % and 0.54 % for 10 replicate determinations. Based on the mutual validation of dual ratio, the dual-channel ratiometric sensing possesses good accuracy, sensitivity, selectivity, and precision. Moreover, ROX can be applied to HClO monitoring in actual water and disinfectant samples with the recoveries of spiked HClO ranged from 95.0 % to 104.2 %. The proposed sensing method highlights the great potential of organic cage in fluorescence sensing.
The high-performance detection of hypochlorous acid (HClO) is crucial for life and environmental health, but still challenging for the single fluorescence signal and single sensing channel of probes. Organic cage with strong adsorption ability and cage structure-related fluorescence property, is a type of potential fluorescent probe. However, the single signal and short emission of organic cage hinders its sensing performance. The design of dual emitting organic cage with long wavelength for dual-channel ratiometric sensing of HClO is of great significance. Herein, we reported an organic cage (ROX) as a probe for accurate quantification of HClO. The prepared ROX exhibited capsule topology-facilitated red/green dual emission around 660/502 nm. The cage-like structure was disrupted by the rapid specific redox interaction between imine bond in ROX and HClO. As a result, the fluorescence at 660 nm quenched in conjunction with the enhancement at 502 nm in PBS (pH 4). Besides, the fluorescence increased at 582 nm with constant emission at 480 nm in DMSO/PBS (pH 7) ( V / V , 9/1). The ratio signal in PBS and DMSO/PBS respectively gave the linearity range of 1–30 and 20–45 μM, the limit of detection (3 s ) of 14 and 49 nM, and the relative standard deviation of 1.04 % and 0.54 % for 10 replicate determinations. Based on the mutual validation of dual ratio, the dual-channel ratiometric sensing possesses good accuracy, sensitivity, selectivity, and precision. Moreover, ROX can be applied to HClO monitoring in actual water and disinfectant samples with the recoveries of spiked HClO ranged from 95.0 % to 104.2 %. The proposed sensing method highlights the great potential of organic cage in fluorescence sensing.
期刊：
Research on Chemical Intermediates,2025年51(9):4829-4848 ISSN：0922-6168
通讯作者：
Ni, WJ
作者机构：
[Yang, Zhiyong; Yan, Jiaqi] Changde Coll, Coll Pharm, Changde 415000, Peoples R China.;[Yang, Qian; Li, Lu; Ni, Wenjin; Fu, Jinfeng] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;[Ni, Wenjin] Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421008, Peoples R China.;[Chen, Wenkai] China Coal Res Inst Corp Ltd, Beijing 100013, Peoples R China.
通讯机构：
[Ni, WJ ] H;Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421008, Peoples R China.
关键词：
N -cyclohexylcyclohexanimine;Cyclohexanone oxime;Ti-based catalyst;Cyclohexylamine;Catalytic oxidation
摘要：
N-cyclohexylcyclohexanimine (N-CCA), a by-product of cyclohexylamine (CHA) oxidation to cyclohexanone oxime (CHO), was used as the starting reactant for the efficient conversion to CHO under an oxygen atmosphere, utilizing the constructed surface hydroxyl-rich Ti-based catalysts. Of these, the 20% TiO2/H beta catalyst exhibited unique catalytic activity and stability, achieving 45.9% N-CCA conversion and 82.1% CHO selectivity, with the content of high-boiling by-products not exceeding 1.0%. The superior catalytic performance, as evidenced by characterization results, stems primarily from: (i) the combination of TiO2 and H beta, which promotes the formation of a high specific surface area with fine TiO2 nanoparticles and high-density Ti delta+ active sites, which facilitate the adsorption and activation of N-CCA; (ii) the construction of rich hydroxyl groups, which enhances the Br & oslash;nsted acid sites, thereby improving the generation of active oxygen species; (iii) the intercrystalline embedding of TiO2 and H beta, which forms Ti-O-Si bonds, effectively inhibiting Ti leaching and ensuring excellent catalyst stability. The conversion of N-CCA, the main by-product of CHA oxidation, to the desired CHO using an efficient and robust 20% TiO2/H beta catalyst represents an attractive pathway.
摘要：
To synthetize a novel hollow nano-tubular Ni 3 S 4 /Co 3 S 4 , we employed a two-stage ion exchange process that included a precursor of cobalt chloride hexahydrate, sodium sulfide for anion exchange, and nickel chloride for cation exchange. The suspension of graphene oxide (GO) and Ni 3 S 4 /Co 3 S 4 was prepared by ultrasonic oscillation. After drying on a glassy carbon electrode (GCE) surface, the nanocomposites were subjected to potentiostatic reduction, effectively transforming GO into electrochemically reduced graphene oxide (ErGO). Characterization of the Ni 3 S 4 /Co 3 S 4 -ErGO nanocomposite by XRD, XPS, EDS and SEM has validated its effective synthesis. It was on this modified electrode (Ni 3 S 4 /Co 3 S 4 -ErGO/GCE) that the electrochemical detection of vanillin was investigated. Second derivative linear sweep voltammetry (SDLSV) was employed to determine the concentration of vanillin. Appropriate determination conditions have been optimized to improve sensitivity. The oxidation peak current of vanillin was approximately 88 times greater on the Ni 3 S 4 /Co 3 S 4 -ErGO/GCE compared to the bare GCE. Within the concentration range of 0.02–20 μM, a robust linear correlation was seen between the peak current and vanillin concentration. A limit of detection (LOD) of 0.8 nM was determined. Additional evaluations included stability, interference, repeatability and reproducibility. This sensor facilitated the detection of vanillin in various food samples.
To synthetize a novel hollow nano-tubular Ni 3 S 4 /Co 3 S 4 , we employed a two-stage ion exchange process that included a precursor of cobalt chloride hexahydrate, sodium sulfide for anion exchange, and nickel chloride for cation exchange. The suspension of graphene oxide (GO) and Ni 3 S 4 /Co 3 S 4 was prepared by ultrasonic oscillation. After drying on a glassy carbon electrode (GCE) surface, the nanocomposites were subjected to potentiostatic reduction, effectively transforming GO into electrochemically reduced graphene oxide (ErGO). Characterization of the Ni 3 S 4 /Co 3 S 4 -ErGO nanocomposite by XRD, XPS, EDS and SEM has validated its effective synthesis. It was on this modified electrode (Ni 3 S 4 /Co 3 S 4 -ErGO/GCE) that the electrochemical detection of vanillin was investigated. Second derivative linear sweep voltammetry (SDLSV) was employed to determine the concentration of vanillin. Appropriate determination conditions have been optimized to improve sensitivity. The oxidation peak current of vanillin was approximately 88 times greater on the Ni 3 S 4 /Co 3 S 4 -ErGO/GCE compared to the bare GCE. Within the concentration range of 0.02–20 μM, a robust linear correlation was seen between the peak current and vanillin concentration. A limit of detection (LOD) of 0.8 nM was determined. Additional evaluations included stability, interference, repeatability and reproducibility. This sensor facilitated the detection of vanillin in various food samples.
作者机构：
[Liu, Wanxin; Li, Wen; Yin, Di; Li, Yi; Wu, Yijin] Hengyang Normal Univ, Coll Chem & Mat Sci, Hunan Engn Res Ctr Monitoring & Treatment Heavy Me, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421001, Peoples R China.
通讯机构：
[Wu, YJ ] H;Hengyang Normal Univ, Coll Chem & Mat Sci, Hunan Engn Res Ctr Monitoring & Treatment Heavy Me, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421001, Peoples R China.
关键词：
5-hydroxymethylfurfural;heterogeneous catalyst;nickel-cobalt compounds;electrochemical performance;active species
摘要：
The electrochemical oxidation of biomass-derived 5-hydroxymethylfurfural (HMF) coupled with water electrolysis for green hydrogen production is a promising strategy to address energy crises and environmental pollution. Despite the suitable adsorption energy for HMF due to their partially filled d-band electronic structures, Ni- or Co-based oxides/hydroxides still face challenges in insufficient activity and stability. In this study, a porous heterogeneous nickel cobalt oxide/hydroxide growth on nickel foam (NF), which is defined as NF@NiCo-H/O, was developed via immersion in concentrated alkali solution. Compared with the single-component NiCo oxides, the NF@NiCo-H/O catalyst exhibits a lower application potential of only 1.317 V, 1.395 V, and 1.443 V to achieve current densities of 20, 50, and 100 mA cm-2, respectively, in an alkaline solution containing HMF. Additionally, it demonstrates rapid reaction kinetics with a Tafel slope of 27.6 mV dec-1 and excellent cycling stability. Importantly, the presence of more high-valent Ni3+-O species on the catalyst surface contributes to its exceptional selectivity for 2,5-furandicarboxylic acid (86.7%), Faradaic efficiency (93.1%), and conversion rate (94.4%). This catalyst provides some theoretical guidance for the development of biomass electrooxidation catalysts for sustainable energy and chemical production.
期刊：
Journal of Alloys and Compounds,2025年1041:183871 ISSN：0925-8388
通讯作者：
Wang, Jinshuang;Jing, QS
作者机构：
[Tian, Yongshang; Xu, Yiyan; Lu, Xianjun; Jing, Qiangshan; Ke, Shunan; Wang, Yinghui; Zhang, Meng; Wang, Jinshuang] Xinyang Normal Univ, Henan Key Lab Utilizat Nonmet Mineral South Henan, Xinyang 464000, Peoples R China.;[Sun, Junbin] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.
通讯机构：
[Wang, JS; Jing, QS ] X;Xinyang Normal Univ, Henan Key Lab Utilizat Nonmet Mineral South Henan, Xinyang 464000, Peoples R China.
关键词：
Ceramic;CMAS+NaVO3;Corrosion mechanisms;TBCs
摘要：
Five mixed corrosion media with varying CMAS/NaVO₃ ratios (CxV10-x, where x denotes the mass percentage of CMAS) were designed in this study and coupled corrosion tests were conducted on Gd₂(Hf₀.₇Ce₀.₃)₂O₇ (GH7C3) ceramic bulks at 1200 °C and 1400 °C. The results indicated that the incorporation of NaVO₃ influences on the self-crystallization behavior of CMAS. Its depolymerization effect enhances the fluidity of CMAS, thereby accelerating the corrosion process of GH7C3 ceramics by the CxV10-x mixed media. Regarding corrosion products, distinct variations were observed: the corrosion product formed in the C0V10/GH7C3 system was identified as GdVO₄, whereas apatite was the dominant corrosion product in other CxV10-x/GH7C3 systems. As the temperature increased to 1400 °C, the types of corrosion products remained relatively unchanged; however, the quantity of self-crystallized products decreased significantly compared to that at 1200 °C. This suggests that temperature affects the precipitation of self-crystallized products in the CxV10-x/GH7C3 systems. Furthermore, an increase in corrosion temperature led to a significant increase in the corrosion depth of GH7C3 ceramics. At 1400 °C, through-thickness corrosion occurred, accompanied by cracking and spalling.
Five mixed corrosion media with varying CMAS/NaVO₃ ratios (CxV10-x, where x denotes the mass percentage of CMAS) were designed in this study and coupled corrosion tests were conducted on Gd₂(Hf₀.₇Ce₀.₃)₂O₇ (GH7C3) ceramic bulks at 1200 °C and 1400 °C. The results indicated that the incorporation of NaVO₃ influences on the self-crystallization behavior of CMAS. Its depolymerization effect enhances the fluidity of CMAS, thereby accelerating the corrosion process of GH7C3 ceramics by the CxV10-x mixed media. Regarding corrosion products, distinct variations were observed: the corrosion product formed in the C0V10/GH7C3 system was identified as GdVO₄, whereas apatite was the dominant corrosion product in other CxV10-x/GH7C3 systems. As the temperature increased to 1400 °C, the types of corrosion products remained relatively unchanged; however, the quantity of self-crystallized products decreased significantly compared to that at 1200 °C. This suggests that temperature affects the precipitation of self-crystallized products in the CxV10-x/GH7C3 systems. Furthermore, an increase in corrosion temperature led to a significant increase in the corrosion depth of GH7C3 ceramics. At 1400 °C, through-thickness corrosion occurred, accompanied by cracking and spalling.
作者机构：
[Liu, Xiang; He, Jia; Sun, Wenqi; Wu, Fuling; Sun, Huajun] Wuhan Univ Technol, Sch Mat Sci & Engn, Wuhan 430070, Peoples R China.;[Wu, Fuling; Sun, Huajun] Wuhan Univ Technol, State Key Lab Silicate Mat Architectures, Wuhan 430070, Peoples R China.;[Sun, Wenqi; Sun, Huajun] Adv Ceram Inst Zibo New & High Tech Ind Dev Zone, Zibo 255000, Peoples R China.;[Liu, Xiaofang] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, Wuhan 430070, Peoples R China.;[Xiao, Shibing] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.
通讯机构：
[Sun, HJ ; Liu, XF ] W;Wuhan Univ Technol, Sch Mat Sci & Engn, Wuhan 430070, Peoples R China.;Wuhan Univ Technol, State Key Lab Silicate Mat Architectures, Wuhan 430070, Peoples R China.;Adv Ceram Inst Zibo New & High Tech Ind Dev Zone, Zibo 255000, Peoples R China.;Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, Wuhan 430070, Peoples R China.
摘要：
The potential of hafnia-based ferroelectric materials for Ferroelectric Random Access Memory (FeRAM) applications is limited by the imprint effect, which compromises readout reliability. Here, we systematically investigate the asymmetric imprint behavior in W/Hf(0.5)Zr(0.5)O(2)/W ferroelectric capacitors, demonstrating that the imprint direction correlates directly with the ferroelectric polarization state. Notably, a pre-pulse of specific polarity can temporarily suppress the imprint effect. Combined experimental and theoretical analyses reveal that the directional segregation of oxygen vacancies (V(O)) at the electrode/ferroelectric interface, coupled with their dynamic charge trapping and detrapping processes, constitutes the core mechanism driving the imprint phenomenon. These processes modulate the built-in electric field, resulting in a shift of the coercive voltage. Building on these findings, we propose an oxygen vacancy segregation-charge trapping model that accounts for critical observations, including the dependence of imprint direction on polarization history and its reversible modulation by pre-pulses. Leveraging this model, we introduce three practical strategies for imprint recovery: charge compensation, oxygen vacancy redistribution, and the design of a bidirectional alternating polarization circuit architecture. Experimental results confirm that these approaches markedly enhance the device's resilience to imprinting, offering innovative pathways to address the reliability challenges of hafnia-based FeRAM.
期刊：
International Journal of Biological Macromolecules,2025年320(Pt 3):145752 ISSN：0141-8130
通讯作者：
Liu, Jing;Wang, LJ;Yuan, F
作者机构：
[Liu, Jing; Wang, Lijia; Li, Yang; Zheng, Zefeng; Liu, Yongjie] Zhejiang Univ, Childrens Hosp, Natl Clin Res Ctr Child Hlth, Natl Childrens Reg Med Ctr,Sch Med, Hangzhou 310052, Peoples R China.;[Liu, Jing; Wang, Lijia; Li, Yang; Zheng, Zefeng; Liu, Yongjie] Zhejiang Key Lab Neonatal Dis, Hangzhou 310052, Peoples R China.;[Cui, Ying] Hengyang Normal Univ, Coll Chem & Mat Sci, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421001, Peoples R China.;[Zhang, Boyou] Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Dept Thorac Surg, Hangzhou 310018, Peoples R China.;[Fan, Shanji] Univ South China, Affiliated Hosp 1, Hengyang Med Sch, Dept Breast & Thyroid Surg, Hengyang 421000, Peoples R China.
通讯机构：
[Liu, J; Wang, LJ ; Yuan, F ] Z;Zhejiang Univ, Childrens Hosp, Natl Clin Res Ctr Child Hlth, Natl Childrens Reg Med Ctr,Sch Med, Hangzhou 310052, Peoples R China.;Zhejiang Hosp, Dept Thorac Surg, Hangzhou 310013, Peoples R China.
关键词：
Deuterium;Macromolecules;Raman spectroscopy
摘要：
When macromolecules are exposed to deuterium-rich environments, hydrogen atoms on them undergo hydrogen‑deuterium exchange, which induces a characteristic Raman spectral redshift, providing a robust signature for probing intracellular microenvironments. This review is a comprehensively survey of the diverse applications of Raman spectroscopy of deuterium-labeled macromolecules in biomedicine over recent years. We summarize its utility in bacterial resistance and metabolism investigations, and discuss applications spanning cellular to whole-animal levels.
When macromolecules are exposed to deuterium-rich environments, hydrogen atoms on them undergo hydrogen‑deuterium exchange, which induces a characteristic Raman spectral redshift, providing a robust signature for probing intracellular microenvironments. This review is a comprehensively survey of the diverse applications of Raman spectroscopy of deuterium-labeled macromolecules in biomedicine over recent years. We summarize its utility in bacterial resistance and metabolism investigations, and discuss applications spanning cellular to whole-animal levels.
期刊：
Journal of Electronic Materials,2025年54(1):712-717 ISSN：0361-5235
通讯作者：
Zhang, ZJ
作者机构：
[Zhang, Zhijian; Zhang, ZJ] Hengyang Normal Univ, Key Lab Funct Met Organ Cpds, Hengyang 421001, Peoples R China.;[Zhang, Zhijian; Zhang, ZJ] Hengyang Normal Univ, Key Lab Funct Organometall Mat Hunan Prov, Hengyang 421001, Peoples R China.;[Shi, Wei; Li, Xinghua] Collaborat Innovat Res Inst Hunan Prov, Hunan Prov Sci & Technol Affairs Ctr & Ind Technol, Changsha 410013, Hunan, Peoples R China.
通讯机构：
[Zhang, ZJ ] H;Hengyang Normal Univ, Key Lab Funct Met Organ Cpds, Hengyang 421001, Peoples R China.;Hengyang Normal Univ, Key Lab Funct Organometall Mat Hunan Prov, Hengyang 421001, Peoples R China.
关键词：
Ab initio calculation;magnetic properties;optical properties;two-dimensional gamma-GeSe;electronic properties
摘要：
Using ab initio calculations, the structural and photoelectric properties of gamma-GeSe with B, C, and N adsorption were systematically investigated. The atomic structure relaxations show that B, C, and N are preferentially located on the lower hexagonal hollow, upper hexagonal hollow, and on top of Se, respectively. The adsorption with B, C, and N can induce defective bands between the energy region n of the valence bands and the conduction bands, and all the systems with adatoms are magnetic, with 1 mu(B), 2 mu(B), and 1 mu(B) magnetic moments, respectively, which are mainly caused by the hybridization between adatoms and the adjacent Ge and Se atoms. Based on the spin-polarized band structure, we find that C-adsorbed gamma-GeSe is metallic, while gamma-GeSe with B and N adatoms is half-metallic, with 100% spin polarization at the Fermi level. Furthermore, owing to the electronic structural differences between spin-up and spin-down sections of B- and N-adsorbed gamma-GeSe, the light in the low-energy region (< 1.0 eV) can only cause electronic excitations in one spin channel, giving rise to interesting spin-polarized photoelectric properties. Our results suggest that gamma-GeSe with B, C, and N adsorption is a promising candidate for spintronic photoelectric device applications.
作者机构：
[Zhenhua Song; Xianwen Song] Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, 932 Lushan South Road Yuelu District, Changsha, 410083 China;[Xintao Zhu] State Key Laboratory Incubation Base for Green Processing of Chemical Engineering, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi, 832003 China;State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources, College of Chemistry, Xinjiang University, Urumqi, Xinjiang, 830017 China;State Key Laboratory of Functional Metal–Organic Compounds of Hunan Province, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang, 421008 China;[Qiang Li] State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources, College of Chemistry, Xinjiang University, Urumqi, Xinjiang, 830017 China<&wdkj&>Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, 932 Lushan South Road Yuelu District, Changsha, 410083 China
通讯机构：
[Qiang Li; Yi Zhang] S;State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources, College of Chemistry, Xinjiang University, Urumqi, Xinjiang, 830017 China<&wdkj&>Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, 932 Lushan South Road Yuelu District, Changsha, 410083 China<&wdkj&>State Key Laboratory Incubation Base for Green Processing of Chemical Engineering, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi, 832003 China<&wdkj&>State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources, College of Chemistry, Xinjiang University, Urumqi, Xinjiang, 830017 China<&wdkj&>Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, 932 Lushan South Road Yuelu District, Changsha, 410083 China
关键词：
Acid gel electrolyte;Battery configuration;Hybrid gel;Ionic conductivity;Zinc-air batteries
摘要：
Alkaline zinc-air batteries (ZABs) are recognized as a promising candidate for next generation of safe battery systems, owing to their inherent advantages. However, the performance of traditional ZABs is constrained by a lower theoretical voltage of 1.65 V, presenting a significant challenge in enhancing their practical application. This paper demonstrates a prototype of acid-alkaline hybrid quasi-solid-state zinc-air battery (HSZAB), featuring a unique design in both a new acidic gel electrolyte and battery structure. Our approach involves regulating the electrolyte pH and ionic conductivity to achieve an enhanced theoretical voltage, resulting in an open circuit voltage of up to 2.0 V. Additionally, the HSZAB demonstrates substantially improved peak power density (417 mW cm −2 , five times higher than the conventional alkaline ZABs) and increased energy efficiency (from 60% to 82%). This finding underscores the promising prospects of high voltage zinc-air batteries, offering a substantial step forward in the field of energy storage systems.
摘要：
The accurate and sensitive quantification of hydroxyl radical (·OH) and glucose is necessary for disease diagnosis and health guidance, but still challenging owing to the low concentration of ·OH and poor water solubility of fluorescent probes. In addition, fluorescent probes may cause secondary pollution to the environment. Here an organic cage was reported as a sensitive fluorescent probe for ·OH and glucose in aqueous solution without serious secondary pollution. The prepared organic cage with good water solubility showed specific redox affinity to ·OH in acidic condition, resulting in two oxidation stages of mild oxidation and subsequent oxidative degradation. Fluorescence around 485 nm enhanced remarkably in the first stage, and benzene ring in organic cage was degraded in the second stage. Based on the significant fluorescence enhancement, a sensitive fluorescence turn-on sensing method for ·OH was established within 90 s with the limit of detection (3 s/k , where s and k are the standard deviation for 10 replicate detections of blank and the slope of calibration function) of 5 nM. The recoveries of spiked ·OH in human serum and water samples ranged from 95.2 % to 102.7 %. After the glucose oxidase enzyme-Fenton reaction was involved, the ·OH detection was also applied to sensitive sensing of glucose with the limit of detection (3 s/k ) of 6 nM. The recoveries of spiked glucose in sugary drinks ranged from 96.2 % to 102.6 %. Furthermore, the proposed method would also be suitable for other hazardous substances and biomarkers which can produce hydrogen peroxide and further form ·OH via Fenton reaction.
The accurate and sensitive quantification of hydroxyl radical (·OH) and glucose is necessary for disease diagnosis and health guidance, but still challenging owing to the low concentration of ·OH and poor water solubility of fluorescent probes. In addition, fluorescent probes may cause secondary pollution to the environment. Here an organic cage was reported as a sensitive fluorescent probe for ·OH and glucose in aqueous solution without serious secondary pollution. The prepared organic cage with good water solubility showed specific redox affinity to ·OH in acidic condition, resulting in two oxidation stages of mild oxidation and subsequent oxidative degradation. Fluorescence around 485 nm enhanced remarkably in the first stage, and benzene ring in organic cage was degraded in the second stage. Based on the significant fluorescence enhancement, a sensitive fluorescence turn-on sensing method for ·OH was established within 90 s with the limit of detection (3 s/k , where s and k are the standard deviation for 10 replicate detections of blank and the slope of calibration function) of 5 nM. The recoveries of spiked ·OH in human serum and water samples ranged from 95.2 % to 102.7 %. After the glucose oxidase enzyme-Fenton reaction was involved, the ·OH detection was also applied to sensitive sensing of glucose with the limit of detection (3 s/k ) of 6 nM. The recoveries of spiked glucose in sugary drinks ranged from 96.2 % to 102.6 %. Furthermore, the proposed method would also be suitable for other hazardous substances and biomarkers which can produce hydrogen peroxide and further form ·OH via Fenton reaction.
作者机构：
[Chenguang Li] College of Chemistry and Material Science, Hengyang Normal University, Hengyang, 421008, PR China;Hunan Province Key Laboratory of Functional Metal-Organic Compounds (Hengyang Normal University), Hengyang, 421008, PR China;Key Laboratory of Organometallic New Materials (Hengyang Normal University), College of Hunan Province, Hengyang, 421008, PR China;Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River (Hengyang Normal University), Hengyang, 421008, PR China;[Junbin Sun; Weihong Lu] College of Chemistry and Material Science, Hengyang Normal University, Hengyang, 421008, PR China<&wdkj&>Hunan Province Key Laboratory of Functional Metal-Organic Compounds (Hengyang Normal University), Hengyang, 421008, PR China<&wdkj&>Key Laboratory of Organometallic New Materials (Hengyang Normal University), College of Hunan Province, Hengyang, 421008, PR China<&wdkj&>Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River (Hengyang Normal University), Hengyang, 421008, PR China
通讯机构：
[Junbin Sun] C;College of Chemistry and Material Science, Hengyang Normal University, Hengyang, 421008, PR China<&wdkj&>Hunan Province Key Laboratory of Functional Metal-Organic Compounds (Hengyang Normal University), Hengyang, 421008, PR China<&wdkj&>Key Laboratory of Organometallic New Materials (Hengyang Normal University), College of Hunan Province, Hengyang, 421008, PR China<&wdkj&>Hunan Engineering Research Center for Monitoring and Treatment of Heavy Metals Pollution in the Upper Reaches of Xiangjiang River (Hengyang Normal University), Hengyang, 421008, PR China
摘要：
The corrosion caused by air sediments comprising CaO-MgO-Al 2 O 3 -SiO 2 (CMAS) poses a notable challenge to thermal/environmental barrier coatings as engine service temperatures continue to rise. In this study, three types of Y 2 O 3 -SiO 2 binary compound ceramic bulks—Y 2 SiO 5 , Y 2 SiO 5 -Y 2 Si 2 O 7 and Y 2 Si 2 O 7 —with molar ratios of Y 2 O 3 :SiO 2 of 1:1, 1:1.5, and 1:2, respectively, were prepared and subjected to CMAS corrosion at 1250 °C and 1350 °C for durations ranging from 1 to 10 h. The corrosion products and cross-sectional morphologies of the samples were characterized using X-ray diffraction and scanning electron microscope. The results demonstrate that the material composition determines its CMAS corrosion behavior. Y 2 SiO 5 , with higher Y 2 O 3 content, consumes more CaO to form Ca 2 Y 8 (SiO 4 ) 6 O 2 , thereby reducing the CaO content and increasing the viscosity of the residual CMAS melt. This process inhibits further CMAS penetration. The findings highlight a novel strategy to improve CMAS corrosion resistance by modifying the CMAS composition and reducing its penetration capability.
The corrosion caused by air sediments comprising CaO-MgO-Al 2 O 3 -SiO 2 (CMAS) poses a notable challenge to thermal/environmental barrier coatings as engine service temperatures continue to rise. In this study, three types of Y 2 O 3 -SiO 2 binary compound ceramic bulks—Y 2 SiO 5 , Y 2 SiO 5 -Y 2 Si 2 O 7 and Y 2 Si 2 O 7 —with molar ratios of Y 2 O 3 :SiO 2 of 1:1, 1:1.5, and 1:2, respectively, were prepared and subjected to CMAS corrosion at 1250 °C and 1350 °C for durations ranging from 1 to 10 h. The corrosion products and cross-sectional morphologies of the samples were characterized using X-ray diffraction and scanning electron microscope. The results demonstrate that the material composition determines its CMAS corrosion behavior. Y 2 SiO 5 , with higher Y 2 O 3 content, consumes more CaO to form Ca 2 Y 8 (SiO 4 ) 6 O 2 , thereby reducing the CaO content and increasing the viscosity of the residual CMAS melt. This process inhibits further CMAS penetration. The findings highlight a novel strategy to improve CMAS corrosion resistance by modifying the CMAS composition and reducing its penetration capability.
期刊：
Sensors and Actuators B-Chemical,2025年442:138164 ISSN：0925-4005
通讯作者：
Li, JH;Qian, D;Waterhouse, GIN
作者机构：
[Feng, Hao; Wang, Yu; Li, Junhua; Zhan, Huimin; Wang, Fan; Liao, Huiyang; Long, Ruiqing; Zhu, Jiacheng] Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;[Liu, Jinlong; Qian, Dong] Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China.;[Waterhouse, Geoffrey I. N.] Univ Auckland, Sch Chem Sci, Auckland 1142, New Zealand.
通讯机构：
[Li, JH ] H;[Qian, D ] C;[Waterhouse, GIN ] U;Hengyang Normal Univ, Coll Chem & Mat Sci, Hengyang 421008, Peoples R China.;Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China.
关键词：
Prussian blue analogue;Bimetal/nitrogen-doped carbon composite;Multifunctional nanozyme;Dual-mode colorimetric-electrochemical;sensing
摘要：
Robust nanozymes with high activities and multifunctional catalytic properties are highly sought by the sensing community as replacements for delicate natural enzymes. Herein, we report the discovery of a multifunctional nanozyme comprising Mn 3 Fe 2.7 C nanoparticles encapsulated by nitrogen-doped carbon shells embedded with carbon nanotubes (Mn 3 Fe 2.7 C@C (700) ), prepared by pyrolysis of a Prussian blue analogue (specifically KMnFe(CN) 6 ·2 H 2 O) at 700 °C in N 2 . Due to synergy between the Mn 3 Fe 2.7 C nanoparticles and the distinctive nitrogen-doped carbon configuration, Mn 3 Fe 2.7 C@C (700) exhibits four exceptional catalytic activities including dual-enzyme oxidase-like and peroxidase-like activities along with bifunctional electrocatalytic activities for oxidation and reduction reactions. Leveraging these advantages, a dual-mode sensing strategy was proposed for dopamine (DA) and H 2 O 2 utilizing colorimetric and electrochemical signal readouts, enabling accurate real-time monitoring of both analytes. In colorimetric and electrochemical sensing modes, the linear ranges are 1.0–80.0 and 2.0–233.0 μM for DA, respectively, and 4.0–200.0 and 100.0–8650.0 μM for H 2 O 2 , respectively. Corresponding detection limits are 0.44 and 1.21 μM for DA, and 0.29 and 13.37 μM for H 2 O 2 . Furthermore, the Mn 3 Fe 2.7 C@C (700) nanozyme was successfully applied for the determination of DA and H 2 O 2 in milk, synthetic urine and sweat, and commercial detergents, achieving satisfactory recoveries ranging from 87.6 % to 112.9 % (with < 3 % deviation across the different detection modes). This work encourages the wide application of nanozymes for multi-modal sensing of target analytes.
Robust nanozymes with high activities and multifunctional catalytic properties are highly sought by the sensing community as replacements for delicate natural enzymes. Herein, we report the discovery of a multifunctional nanozyme comprising Mn 3 Fe 2.7 C nanoparticles encapsulated by nitrogen-doped carbon shells embedded with carbon nanotubes (Mn 3 Fe 2.7 C@C (700) ), prepared by pyrolysis of a Prussian blue analogue (specifically KMnFe(CN) 6 ·2 H 2 O) at 700 °C in N 2 . Due to synergy between the Mn 3 Fe 2.7 C nanoparticles and the distinctive nitrogen-doped carbon configuration, Mn 3 Fe 2.7 C@C (700) exhibits four exceptional catalytic activities including dual-enzyme oxidase-like and peroxidase-like activities along with bifunctional electrocatalytic activities for oxidation and reduction reactions. Leveraging these advantages, a dual-mode sensing strategy was proposed for dopamine (DA) and H 2 O 2 utilizing colorimetric and electrochemical signal readouts, enabling accurate real-time monitoring of both analytes. In colorimetric and electrochemical sensing modes, the linear ranges are 1.0–80.0 and 2.0–233.0 μM for DA, respectively, and 4.0–200.0 and 100.0–8650.0 μM for H 2 O 2 , respectively. Corresponding detection limits are 0.44 and 1.21 μM for DA, and 0.29 and 13.37 μM for H 2 O 2 . Furthermore, the Mn 3 Fe 2.7 C@C (700) nanozyme was successfully applied for the determination of DA and H 2 O 2 in milk, synthetic urine and sweat, and commercial detergents, achieving satisfactory recoveries ranging from 87.6 % to 112.9 % (with < 3 % deviation across the different detection modes). This work encourages the wide application of nanozymes for multi-modal sensing of target analytes.
通讯机构：
[Chen, W ] H;Hengyang Normal Univ, Coll Chem & Mat Sci, Key Lab Funct Organometall Mat, Coll Hunan Prov, Hengyang 421008, Peoples R China.
关键词：
G4s;ROS;Fluorescence imaging;Flow cytometry
摘要：
Endogenous G-quadruplexes (G4s) and reactive oxygen species (ROS) form a complex regulatory network in tumors, and their interaction is both a key link in tumor development and provides a breakthrough for the development of new diagnostic and therapeutic approaches. Although reports on the activation of G4s fluorescent probes are common, fluorescent probes suitable for studying the relationship between intracellular G4s and ROS are extremely rare. In this work, we successfully synthesized a series of novel neutral G4s-targeting molecules (PMT, PNB, PMI, and PMD). In vitro analysis experiments revealed that PMT, PNB, PMI, and PMD can be selectively activated by G4 structures, with their fluorescence intensities enhanced by 75-fold, 31-fold, 32-fold, and 3-fold, respectively. Molecular docking experiments have shown that small molecules are predominantly embedded within nucleic acids and stabilize the basis of binding through hydrogen bonding and Π-hydrogen interactions with nucleic acids. Moreover, confocal fluorescence imaging and flow cytometry (FC) analyses revealed the expression of intracellular G4s may be an increase under ROS conditions, further verifying that ROS may promote the formation of intracellular G4s by experiments in which the cells were made to generate endogenous reactive oxygen species through light exposure to the photosensitizer (BAMA). In the present work, a platform for simple and convenient accurate monitoring of G4s is provided, offering insights into the sensitivity and accuracy of detection and imaging of G4s in abnormal physiological processes and diseases.
Endogenous G-quadruplexes (G4s) and reactive oxygen species (ROS) form a complex regulatory network in tumors, and their interaction is both a key link in tumor development and provides a breakthrough for the development of new diagnostic and therapeutic approaches. Although reports on the activation of G4s fluorescent probes are common, fluorescent probes suitable for studying the relationship between intracellular G4s and ROS are extremely rare. In this work, we successfully synthesized a series of novel neutral G4s-targeting molecules (PMT, PNB, PMI, and PMD). In vitro analysis experiments revealed that PMT, PNB, PMI, and PMD can be selectively activated by G4 structures, with their fluorescence intensities enhanced by 75-fold, 31-fold, 32-fold, and 3-fold, respectively. Molecular docking experiments have shown that small molecules are predominantly embedded within nucleic acids and stabilize the basis of binding through hydrogen bonding and Π-hydrogen interactions with nucleic acids. Moreover, confocal fluorescence imaging and flow cytometry (FC) analyses revealed the expression of intracellular G4s may be an increase under ROS conditions, further verifying that ROS may promote the formation of intracellular G4s by experiments in which the cells were made to generate endogenous reactive oxygen species through light exposure to the photosensitizer (BAMA). In the present work, a platform for simple and convenient accurate monitoring of G4s is provided, offering insights into the sensitivity and accuracy of detection and imaging of G4s in abnormal physiological processes and diseases.
期刊：
Results in Engineering,2025年26:105171 ISSN：2590-1230
通讯作者：
Quanguo He
作者机构：
[Deng, Peihong] Hengyang Normal Univ, Dept Chem & Mat Sci, Key Lab Organometall New Mat, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421008, Peoples R China.;[He, Quanguo; Chen, Aiting; Zhou, Chuanqin; Tang, Nana; Shi, Shuting; He, QG] Hunan Univ Technol, Coll Life Sci & Chem, Zhuzhou 412007, Peoples R China.
通讯机构：
[He, QG ] H;Hunan Univ Technol, Coll Life Sci & Chem, Zhuzhou 412007, Peoples R China.
关键词：
Co 9 S 8;Reduced graphene oxide;Electrochemical detection;Tryptophan;Uric acid;Dopamine
摘要：
A cost-effective and simple electrochemical approach was developed for the simultaneous detection of tryptophan (Trp), uric acid (UA) and dopamine (DA). Through hydrothermal synthesis, Co 9 S 8 was combined with graphene oxide (GO) using physical ultrasound. Subsequently, the Co 9 S 8 -RGO/GCE was created by electrochemically reducing a Co 9 S 8 -GO dispersion after drop-coating it onto the GCE surface. The amalgamation of Co 9 S 8 with RGO conferred the sensor with remarkable sensitivity, outstanding selectivity, and robust catalytic prowess towards DA, UA and Trp. The ternary mixture exhibited notable peak separations of up to 160 mV, 278 mV, and 438 mV between DA–UA, UA–Trp, and DA–Trp, respectively. The linear calibration ranges spanned 0.1–2.0 μM and 2.0–10 μM for DA, 0.06–10 μM for UA, and 0.02–10 μM for Trp, with matching 0.04 µM for DA, 0.02 µM for UA, and 6.0 nM for Trp detection limits (S/ N = 3). Moreover, the sensor's effective use in the identification of DA, UA and Trp in authentic samples yielded satisfactory results.
A cost-effective and simple electrochemical approach was developed for the simultaneous detection of tryptophan (Trp), uric acid (UA) and dopamine (DA). Through hydrothermal synthesis, Co 9 S 8 was combined with graphene oxide (GO) using physical ultrasound. Subsequently, the Co 9 S 8 -RGO/GCE was created by electrochemically reducing a Co 9 S 8 -GO dispersion after drop-coating it onto the GCE surface. The amalgamation of Co 9 S 8 with RGO conferred the sensor with remarkable sensitivity, outstanding selectivity, and robust catalytic prowess towards DA, UA and Trp. The ternary mixture exhibited notable peak separations of up to 160 mV, 278 mV, and 438 mV between DA–UA, UA–Trp, and DA–Trp, respectively. The linear calibration ranges spanned 0.1–2.0 μM and 2.0–10 μM for DA, 0.06–10 μM for UA, and 0.02–10 μM for Trp, with matching 0.04 µM for DA, 0.02 µM for UA, and 6.0 nM for Trp detection limits (S/ N = 3). Moreover, the sensor's effective use in the identification of DA, UA and Trp in authentic samples yielded satisfactory results.
摘要：
A novel nickel foam supported NiFe 2 O 4 /NiO (NiFe 2 O 4 /NiO/NF) catalyst was prepared using one-step hydrothermal synthesis followed by calcination, and subsequently applied to the Catalytic Wet Peroxide Oxidation (CWPO) of Acid Orange 7 (AO7) in a continuous fixed bed system. The physicochemical properties of NiFe 2 O 4 /NiO/NF were characterized via XRD, XPS, SEM, and Raman, revealing that interconnected sheet-like NiFe 2 O 4 /NiO nanosheets with an ultra-thin structure and channel-opening characteristics were uniformly coated on the surface of NF. Remarkably, NiFe 2 O 4 /NiO/NF exhibited exceptional catalytic activity toward AO7 degradation under optimized conditions: urea/metal molar ratio of 5:1, hydrothermal reaction time of 6 h, and Fe/Ni concentration of 20/20 mM. At the reaction temperature of 70 °C, pH 2.0, space velocity of 0.265 min −1 , and AO7 concentration of 50 mg/L, the AO7 conversion remained stable (>99.0 %) over 240 min, while COD removal ratios were 57.9 %, 66.4 %, 48.8 % and 47.9 % when the fixed bed system was continuously run for 60, 120, 180 and 240 min, respectively. After three consecutive cycles, AO7 conversion ratios at 240 min were 99.2 %, 98.8 %, and 98.4 %, with a total decrease of less than 1 %. DFT calculations indicated that the NiFe 2 O 4 /NiO catalyst, owing to the Fe/Ni bimetallic synergy, facilitated O-O bond cleavage in H 2 O 2 and HO· radical formation more effectively than Fe 2 O 3 or NiO alone.
A novel nickel foam supported NiFe 2 O 4 /NiO (NiFe 2 O 4 /NiO/NF) catalyst was prepared using one-step hydrothermal synthesis followed by calcination, and subsequently applied to the Catalytic Wet Peroxide Oxidation (CWPO) of Acid Orange 7 (AO7) in a continuous fixed bed system. The physicochemical properties of NiFe 2 O 4 /NiO/NF were characterized via XRD, XPS, SEM, and Raman, revealing that interconnected sheet-like NiFe 2 O 4 /NiO nanosheets with an ultra-thin structure and channel-opening characteristics were uniformly coated on the surface of NF. Remarkably, NiFe 2 O 4 /NiO/NF exhibited exceptional catalytic activity toward AO7 degradation under optimized conditions: urea/metal molar ratio of 5:1, hydrothermal reaction time of 6 h, and Fe/Ni concentration of 20/20 mM. At the reaction temperature of 70 °C, pH 2.0, space velocity of 0.265 min −1 , and AO7 concentration of 50 mg/L, the AO7 conversion remained stable (>99.0 %) over 240 min, while COD removal ratios were 57.9 %, 66.4 %, 48.8 % and 47.9 % when the fixed bed system was continuously run for 60, 120, 180 and 240 min, respectively. After three consecutive cycles, AO7 conversion ratios at 240 min were 99.2 %, 98.8 %, and 98.4 %, with a total decrease of less than 1 %. DFT calculations indicated that the NiFe 2 O 4 /NiO catalyst, owing to the Fe/Ni bimetallic synergy, facilitated O-O bond cleavage in H 2 O 2 and HO· radical formation more effectively than Fe 2 O 3 or NiO alone.
作者机构：
[Jiang, Wujiu; Tan, Jing; Tan, Yuxing; Ni, Penghui] Hengyang Normal Univ, Coll Chem & Mat Sci, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421008, Hunan, Peoples R China.;[Deng, Guo-Jun] Xiangtan Univ, Coll Chem,Minist Educ, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environmentally Friendly Chem & Applicat, Xiangtan 411105, Peoples R China.
通讯机构：
[Ni, PH ] H;[Deng, GJ ] X;Hengyang Normal Univ, Coll Chem & Mat Sci, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421008, Hunan, Peoples R China.;Xiangtan Univ, Coll Chem,Minist Educ, Key Lab Green Organ Synth & Applicat Hunan Prov, Key Lab Environmentally Friendly Chem & Applicat, Xiangtan 411105, Peoples R China.
摘要：
Herein, we report that a metal-free multicomponent strategy integrates Kornblum oxidation, dehydrative condensation, Willgerodt–Kindler-type polysulfuration, and heterocyclization, enabling the synthesis of bioactive 1,2,3-dithiazole-5-thione scaffolds from readily accessible methyl ketones, elemental sulfur, and cyanamides. In this protocol, S 8 serves as the triple sulfur donor for both the CS and S 2 moieties, while cyanamides provide the nitrogen source. Remarkably, this method accomplishes the cleavage of triple Csp 3 H bonds and the formation of multiple Cheteroatom bonds within one step.
Herein, we report that a metal-free multicomponent strategy integrates Kornblum oxidation, dehydrative condensation, Willgerodt–Kindler-type polysulfuration, and heterocyclization, enabling the synthesis of bioactive 1,2,3-dithiazole-5-thione scaffolds from readily accessible methyl ketones, elemental sulfur, and cyanamides. In this protocol, S 8 serves as the triple sulfur donor for both the CS and S 2 moieties, while cyanamides provide the nitrogen source. Remarkably, this method accomplishes the cleavage of triple Csp 3 H bonds and the formation of multiple Cheteroatom bonds within one step.
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通讯作者：
Yi Zhang<&wdkj&>You-Nian Liu<&wdkj&>Qichen Wang
作者机构：
[Yang Chen; Haojie Zhu; Junhua Li; Mengqin Liu] Key Laboratory of Functional Metal–Organic Compounds of Hunan Province, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang, 421008 China;[You-Nian Liu] Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China;[Qichen Wang] Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics, Northwestern Polytechnical University, Xi'an, 710072 China;[Yi Zhang] Key Laboratory of Functional Metal–Organic Compounds of Hunan Province, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang, 421008 China<&wdkj&>Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China
通讯机构：
[Yi Zhang] K;[You-Nian Liu] H;[Qichen Wang] F;Key Laboratory of Functional Metal–Organic Compounds of Hunan Province, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang, 421008 China<&wdkj&>Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China<&wdkj&>Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics, Northwestern Polytechnical University, Xi'an, 710072 China<&wdkj&>Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083 China
摘要：
The electrochemical CO 2 reduction reaction (eCO 2 RR) offers a promising method for sustainable energy conversion, enabling the transformation of electrical energy into chemical energy while achieving carbon neutrality efforts. Among the various electrocatalysts, carbon-supported single-atom catalysts (C-SACs) have garnered significant interest due to their advantages of high atom efficiency, tunable structure, and exceptional catalytic activity. Designing effective C-SACs for eCO 2 RR requires a comprehensive understanding of their structure-property relationship, particularly regarding the dynamic changes of these materials under electrochemical conditions. Despite recently achieved innovative progress, universal design guidelines remain elusive, and the development of ideal catalysts still highly relies on trial-and-error approaches. This review provides a detailed analysis of the real-time structure evolution and mechanisms of C-SACs during eCO 2 RR, integrating various in situ and operando techniques with theoretical analyses. Consequently, nine design strategies aimed at increasing structural heterogeneity through the modification of metal, nitrogen, and carbon components in C-SACs, focusing on specific cases that elucidate the structure-performance relationship, are highlighted. Finally, the existing challenges are addressed, and future directions for the advancement of efficient C-SACs in eCO 2 RR are outlined. This review aspires to illuminate a promising path for researchers aiming to design high-performance C-SACs for sustainable eCO 2 RR initiatives.
