作者机构：
[Yang, Qingshan; Wang, Shuting; Liu, Juan; Xing, SH; Peng, Daiyin; Xing, Shihai; Xu, Shaowei; Meng, Fei] Anhui Univ Chinese Med, Coll Pharm, Hefei 230012, Peoples R China.;[Jiang, Weimin] Hengyang Normal Univ, Coll Life Sci & Environm, Hunan Key Lab Conservat & Utilizat Biol Resources, Hengyang 421008, Hunan, Peoples R China.;[Xing, SH; Peng, Daiyin; Xing, Shihai; Meng, Fei] Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei 230012, Peoples R China.;[Sun, Zongping] Fuyang Normal Univ, Engn Technol Res Ctr Antiaging, Chinese Herbal Med, Fuyang 236037, Peoples R China.;[Xing, SH; Xing, Shihai; Chen, Na] Hefei Comprehens Natl Sci Ctr, Joint Res Ctr Chinese Herbal Med Anhui IHM, Bozhou 236814, Peoples R China.
通讯机构：
[Liu, J; Xing, SH ] A;Anhui Univ Chinese Med, Coll Pharm, Hefei 230012, Peoples R China.;Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei 230012, Peoples R China.;Hefei Comprehens Natl Sci Ctr, Joint Res Ctr Chinese Herbal Med Anhui IHM, Bozhou 236814, Peoples R China.
作者机构：
[He, Lifang] Hengyang Normal Univ, Dept Life Sci, Hengyang 421008, Hunan, Peoples R China.;[Zhu, Xiaoming; He, Lifang; Zhang, Fuxing] Hengyang Normal Univ, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421008, Peoples R China.;[Zhu, Xiaoming; Wu, Yuxuan; Zhang, Fuxing; Tang, Jianxin; Tang, Wenjie; Liang, Mingsheng; Luo, Yaoze] Hengyang Normal Univ, Dept Chem & Mat Sci, Hengyang 421008, Hunan, Peoples R China.;[Zhu, Xiaoming; Zhang, Fuxing] Univ Hunan Prov, Hengyang Normal Univ, Key Lab Organometall New Mat, Hengyang 421008, Hunan, Peoples R China.
通讯机构：
[Zhang, FX ] H;Hengyang Normal Univ, Key Lab Funct Met Organ Cpds Hunan Prov, Hengyang 421008, Peoples R China.;Hengyang Normal Univ, Dept Chem & Mat Sci, Hengyang 421008, Hunan, Peoples R China.;Univ Hunan Prov, Hengyang Normal Univ, Key Lab Organometall New Mat, Hengyang 421008, Hunan, Peoples R China.
作者：
Ji, Li*;Sheng, Song;Shen, Fangyuan;Yang, Lili;Wen, Shizhi;...
期刊：
CATENA,2024年237:107816 ISSN：0341-8162
通讯作者：
Ji, L;Ji, Li;Yang, LX;Wang, X
作者机构：
[He, Gongxiu; Ji, L; Sheng, Song; Ji, Li; Wen, Shizhi; Yang, Lili] Cent South Univ Forestry & Technol, Sch Forestry, Changsha 410004, Peoples R China.;[Ji, Li; Yang, Lixue; Yang, LX; Ji, L; Shen, Fangyuan] Northeast Forestry Univ, Sch Forestry, Key Lab Sustainable Forest Ecosyst Management, Minist Educ, Harbin 150040, Peoples R China.;[Wang, Na] Hengyang Normal Univ, Hunan Prov Key Lab Funct Met Organ Cpds, Hengyang 421008, Peoples R China.;[Wang, Na] Hengyang Normal Univ, Coll Life Sci & Environm, Hengyang 421008, Peoples R China.;[Wang, Xu] Chinese Acad Forestry, Res Inst Trop Forestry, Guangzhou 510520, Peoples R China.
通讯机构：
[Ji, L ; Wang, X ] C;[Yang, LX ; Ji, L] N;Cent South Univ Forestry & Technol, Sch Forestry, Changsha 410004, Peoples R China.;Northeast Forestry Univ, Sch Forestry, Key Lab Sustainable Forest Ecosyst Management, Minist Educ, Harbin 150040, Peoples R China.;Chinese Acad Forestry, Res Inst Trop Forestry, Guangzhou 510520, Peoples R China.
关键词：
Da Hinggan Mountains;altitude;boreal forest;microbial activity;microbial community;relative abundance;seasonal variation;soil microorganism;stochasticity
摘要：
Soil bacteria, as integral components of the soil microbial community, play pivotal roles in biogeochemical cycles and ecosystem functions in boreal forests. The altitudinal patterns of soil bacteria have been widely reported, but their community assembly is uncertain. Here, we investigated the soil bacterial community attributes (diversity, taxonomic and functional composition, and bacterial interactions) and ecological processes associated with community assembly on Mt. Oakley in the northern Greater Khingan Mountains via Illumina MiSeq sequencing and functional annotation tools. The alpha diversity indices of the soil bacteria exhibited a progressively decreasing trend with increasing altitude across seasons. The relative abundance of the dominant bacterial taxa was more sensitive to altitude than to season. More complex (more nodes and links) bacterial interactions were detected at the lowest and highest altitudinal sites, as well as in September. The variations in the taxonomic and functional compositions of the soil bacteria induced by altitude were mainly driven by the variations in soil pH and extracellular enzyme activities. Stochastic (dispersal limitation and drift) processes largely controlled the soil bacterial community assemblages across spatiotemporal scales. The community assemblages of soil bacteria were affected by altitude-induced changes in the taxonomic composition and functional groups. Collectively, our results have significant implications for understanding bacterial biogeography and community assembly mechanisms along altitudinal gradients in boreal forest ecosystems.
摘要：
Synthetic lethality is a phenomenon wherein the simultaneous deficiency of two or more genes results in cell death, while the deficiency of any individual gene does not lead to cell death. In recent years, synthetic lethality has emerged as a significant topic in the field of targeted cancer therapy, with certain drugs based on this concept exhibiting promising outcomes in clinical trials. Nevertheless, the presence of tumor heterogeneity and the intricate DNA repair mechanisms pose challenges to the effective implementation of synthetic lethality. This review aims to explore the concepts, development, and ethical quandaries surrounding synthetic lethality. Additionally, it will provide an in-depth analysis of the clinical application and underlying mechanism of synthetic lethality.
Synthetic lethality is a phenomenon wherein the simultaneous deficiency of two or more genes results in cell death, while the deficiency of any individual gene does not lead to cell death. In recent years, synthetic lethality has emerged as a significant topic in the field of targeted cancer therapy, with certain drugs based on this concept exhibiting promising outcomes in clinical trials. Nevertheless, the presence of tumor heterogeneity and the intricate DNA repair mechanisms pose challenges to the effective implementation of synthetic lethality. This review aims to explore the concepts, development, and ethical quandaries surrounding synthetic lethality. Additionally, it will provide an in-depth analysis of the clinical application and underlying mechanism of synthetic lethality.
作者机构：
[Wu, Liping; Wang, Shuting; Guo, Xiaohu; Xing, Shihai; Su, Xinglong; Yao, Xiaoyan; Wang, Zhaojian; Wu, Jing; Zhang, Jing; Meng, Fei] Anhui Univ Chinese Med, Coll Pharm, Hefei 230012, Peoples R China.;[Xing, Shihai; Yao, Xiaoyan] Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei 230012, Peoples R China.;[Sun, Zongping; Qu, Changqing] Fuyang Normal Univ, Anhui Prov Key Lab Environm Hormone & Reprod, Anhui Prov Key Lab Embryo Dev & Reprod Regulat, Fuyang 236037, Peoples R China.;[Jiang, Weimin] Hengyang Normal Univ, Coll Life Sci & Environm, Hunan Key Lab Conservat & Utilizat Biol Resources, Hengyang 421008, Hunan, Peoples R China.;[Wu, Jing] MOE Anhui Joint Collaborat Innovat Ctr Qual Impro, Hefei 230038, Peoples R China.
通讯机构：
[Shihai Xing] C;College of Pharmacy, Anhui Univ. of Chinese Medicine, Hefei, 230012 China<&wdkj&>Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei, 230012 China<&wdkj&>Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei, 230012 China
摘要：
<jats:title>Abstract</jats:title><jats:p>Ginger (<jats:italic>Zingiber officinale</jats:italic> Roscoe) is an important plant used worldwide for medicine and food. The R2R3‐MYB transcription factor (TF) family has essential roles in plant growth, development, and stresses resistance, and the number of genes in the family varies greatly among different types of plants. However, genome‐wide discovery of <jats:italic>ZoMYBs</jats:italic> and gene responses to stresses have not been reported in ginger. Therefore, genome‐wide analysis of R2R3‐MYB genes in ginger was conducted in this study. Protein phylogenetic relations and conserved motifs and chromosome localization and duplication, structure, and <jats:italic>cis</jats:italic>‐regulatory elements were analyzed. In addition, the expression patterns of selected genes were analyzed under two different stresses. A total of 299 candidate <jats:italic>ZoMYB</jats:italic> genes were discovered in ginger. Based on groupings of R2R3‐MYB genes in the model plant <jats:italic>Arabidopsis thaliana</jats:italic> (L.) Heynh., <jats:italic>ZoMYB</jats:italic>s were divided into eight groups. Genes were distributed across 22 chromosomes at uneven densities. In gene duplication analysis, 120 segmental duplications were identified in the ginger genome. Gene expression patterns of 10 <jats:italic>ZoMYB</jats:italic>s in leaves of ginger under abscisic acid (ABA) and low‐temperature stress treatments were different. The results will help to determine the exact roles of <jats:italic>ZoMYB</jats:italic>s in anti‐stress responses in ginger.</jats:p>
通讯机构：
[Wei Liu; Xuexiao Zou] C;[Zhuqing Zhang] V;College of Horticulture, Hunan Agricultural University, Changsha, Hunan 410128, China<&wdkj&>Longping Branch, Graduate School of Hunan University, Changsha, Hunan 410125, Chin<&wdkj&>College of Life Sciences and Environment, Hengyang Normal University, Hengyang, Henan 421008, China<&wdkj&>Vegetable Institution of Hunan Academy of Agricultural Science, Changsha, Hunan 410125, China
作者机构：
[Wang, Zhixin; Cao, Limin; Liu, Jianhui] Hengyang Normal Univ, Coll Life Sci & Environm, Hunan Key Lab Conservat & Utilizat Biol Resources, Hengyang, Hunan, Peoples R China.;[He, Xingjin] Sichuan Univ, Coll Life Sci, Key Lab Bioresources & Ecoenvironm, Minist Educ, Chengdu, Sichuan, Peoples R China.
关键词：
chloroplast DNA;circular DNA;leucine;nadh dehydrogenase subunit 2;plant protein;protein tic 214;ribosomal protein l14;ribosomal protein l16;ribosomal protein l2;ribosomal protein l22;ribosomal protein l23;ribosomal protein l36;ribosomal protein s12;ribosomal protein s3;ribosomal protein s7;ribosomal protein s8;ribosomal protein S9;ribosome RNA;transfer RNA;translation initiation factor if1;unclassified drug;ycf2 protein;Article;China;chloroplast genome;codon usage;complete plastomes;DNA base composition;DNA extraction;DNA sequence;gene number;genetic distance;genome size;high throughput sequencing;inverted repeat boundary;molecular genetic phenomena and functions;nonhuman;phylogeny;Pimpinella;Pimpinella candolleana;Pimpinella diversifolia;Pimpinella purpurea;Pimpinella rhomboidea;Pimpinella rubescens;Pimpinella scaberula;Pimpinella smithii;Pimpinella thellungiana;Pimpinella valleculosa;plant genome;RNA editing site
摘要：
Pimpinella L. is one of the large genera in the Apiaceae family. In a previous study, the molecular phylogenies of Pimpinella were explored using nuclear ribosomal DNA internal transcribed spacers (ITS) and several chloroplast DNA segments. There have been few studies conducted on chloroplast genomes in Pimpinella, which has limited systematic understanding of this genus. We assembled the complete chloroplast genomes of nine Pimpinella species from China using data generated from next generation sequencing (NGS). The chloroplast (cp) DNA used were standard double-stranded molecules, ranging from 146,432 base pairs (bp) (P. valleculosa) to 165,666 bp (P. purpurea) in length. The circular DNA contained a large single-copy (LSC) region, small single-copy (SSC) region, and pair of inverted repeats (IRs). The cp DNA of the nine species contained 82–93 protein-coding genes, 36–37 transfer RNA (tRNA) genes, and eight ribosomal RNA (rRNA) genes, respectively. Four species (P. smithii, P. valleculosa, P. rhomboidea, and P. purpurea) exhibited striking distinctions in genome size, gene number, IR boundary, and sequence identity. We confirmed the nonmonophyly of the Pimpinella species on the basis of the nine newly identified plastomes. The distant relationship between the above-mentioned four Pimpinella species and Pimpinelleae was indicated with high support values. Our study provides a foundation for future in-depth phylogenetic and taxonomic studies of genus Pimpinella. Copyright 2023 Wang et al.
期刊：
Journal of Hazardous Materials,2023年447:130755 ISSN：0304-3894
通讯作者：
Lei, Ming
作者机构：
[Huang, Yayuan; Mensah, Caleb Oppong; Tie, Boqing; Li, Bingyu; Wei, Dongning; Lei, Ming; Zhou, Yimin; Jing, Miaomiao] Hunan Agr Univ, Coll Resource & Environm, Changsha 410128, Peoples R China.;[Huang, Yayuan; Mensah, Caleb Oppong; Tie, Boqing; Li, Bingyu; Lei, Ming; Zhou, Yimin; Jing, Miaomiao] Hunan Engn & Technol Res Ctr Irrigat Water Purific, Changsha 410128, Peoples R China.;[Long, Jiumei] Hengyang Normal Univ, Coll Life Sci & Environm, Hengyang 421008, Peoples R China.;[Lei, Ming] 1st Nongda Rd, Changsha, Peoples R China.
通讯机构：
[Ming Lei] C;College of Resource and Environment, Hunan Agricultural University, Changsha 410128, PR China<&wdkj&>Hunan Engineering and Technology Research Center for Irrigation Water Purification, Changsha 410128, PR China
摘要：
Pseudomonas aeruginosa is a conditional Gram-negative pathogen that produces extracellular virulence factors that can lead to bloodstream invasion, severely harm tissues, and disseminate bacteria, ultimately leading to various diseases. In this study, lactic acid bacteria (LAB) with strong antagonistic ability against P. aeruginosa were screened, and the regulatory mechanism of LAB against P. aeruginosa was evaluated. The results showed that the three selected LAB strains had strong inhibition ability on the growth, biofilm formation, and pyocyanin expression of P. aeruginosa and a promoting effect on the expression of autoinducer-2. Among them, Lactipantibacillus plantarum (Lp. plantarum) LPyang is capable of affecting the metabolic processes of P. aeruginosa by influencing metabolic substances, such as LysoPC, oxidized glutathione, betaine, etc. These results indicate that LPyang reduces the infectivity of P. aeruginosa through inhibition of its growth, biofilm formation, pyocyanin expression, and regulation of its metabolome. This study provides new insights into the antagonistic activity of Lp. plantarum LPyang against P. aeruginosa.
摘要：
Simple Summary Habituation to deterrent plant compounds has been found in generalist and specialist insect herbivores. The rate at which plant-feeding insects habituate and at which sensitivity of taste neurons detecting deterrents changes has not been compared among closely related species. The generalist Helicoverpa armigera (Hubner) and the specialist Helicoverpa assulta (Guenee) (Lepidoptera: Noctuidae) differ strongly in degree of host-plant specialism. Both species habituated to the alkaloid strychnine after dietary exposure; however, the specialist H. assulta displayed habituation to strychnine faster (at 48 h) than the generalist H. armigera (at 72 h). Electrophysiological recordings from taste sensilla on mouthparts revealed that a deterrent-sensitive neuron in the medial sensillum styloconicum of both species displayed significantly reduced sensitivity to the deterrent that coincided in time with the onset of habituation. Our findings show that physiological changes in taste neuron sensitivity coincide with habituation to plant compounds that are initially avoided. The two closely related moth species, Helicoverpa armigera and H. assulta differ strongly in their degree of host-plant specialism. In dual-choice leaf disk assays, caterpillars of the two species that had been reared on standard artificial diet were strongly deterred by the plant-derived alkaloid strychnine. However, caterpillars of both species reared on artificial diet containing strychnine from neonate to the 5th instar were insensitive to this compound. Fifth instar caterpillars of H. assulta and 4th or 5th instars of H. armigera not exposed to strychnine before were subjected to strychnine-containing diet for 24 h, 36 h, 48 h, or 72 h. Whereas H. assulta displayed habituation to strychnine after 48 h, it took until 72 h for H. armigera to become habituated. Electrophysiological tests revealed that a deterrent-sensitive neuron in the medial sensillum styloconicum of both species displayed significantly reduced sensitivity to strychnine that correlated with the onset of habituation. We conclude that the specialist H. assulta habituated faster to strychnine than the generalist H. armigera and hypothesis that desensitization of deterrent-sensitive neurons contributed to habituation.
通讯机构：
[Fengna Li; Yulong Yin] K;Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Science, Changsha, Hunan 410125, China<&wdkj&>Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, Hunan Normal University, Changsha, Hunan 410081, China<&wdkj&>Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Science, Changsha, Hunan 410125, China
摘要：
Detecting and imaging intracellular hypochlorous acid (HClO) is of great importance owning to its prominent role in numerous pathological and physiological processes. In this contribution, a novel AIE-based fluorescent chemosensor has been developed by employing a benzothiazole derivative. The synthesized probe displayed remarkable ratiometric fluorescent response to HClO with a large emission shift (139 nm), resulting in naked-eye fluorescence changes from red to blue. Under the optimal conditions, this probe was capable of quantitatively detecting HClO within 10 s, and possessed good sensitivity and high selectivity toward HClO over other biologically relevant species. Moreover, it has been successfully utilized to image the exogenous and endogenous HClO in living cells through dual channels, and conveniently detect hypochlorous acid solution on test strips with better accuracy, demonstrating its potential for monitoring HClO in biological and environment fields. (c) 2022 Elsevier B.V. All rights reserved.
期刊：
FRONTIERS IN PLANT SCIENCE,2022年13:822374 ISSN：1664-462X
通讯作者：
Peng, Daiyin;Xing, SH;Peng, DY
作者机构：
[Xing, SH; Yao, Liang; Ye, Mengjuan; Xing, Shihai; Yao, Xiaoyan; Wang, Zhaojian; Wu, Jing; Zhang, Jing; Yu, Nianjun; Peng, Daiyin; Meng, Fei; Peng, DY] Anhui Univ Chinese Med, Coll Pharm, Hefei, Peoples R China.;[Xing, SH; Xing, Shihai; Wu, Jing; Yu, Nianjun; Peng, Daiyin; Peng, DY] Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei, Peoples R China.;[Meng, Xiaoxi] Univ Minnesota, Dept Hort Sci, St Paul, MN 55108 USA.;[Jiang, Weimin] Hengyang Normal Univ, Coll Life Sci & Environm, Hunan Key Lab Conservat & Utilizat Biol Resources, Hengyang, Peoples R China.;[Wang, Longhai] Anhui Univ Chinese Med, Sch Integrated Chinese & w Med, Hefei, Peoples R China.
通讯机构：
[Xing, SH ; Peng, DY] A;[Peng, DY ] S;Anhui Univ Chinese Med, Coll Pharm, Hefei, Peoples R China.;Anhui Acad Chinese Med, Inst Tradit Chinese Med Resources Protect & Dev, Hefei, Peoples R China.;Synerget Innovat Ctr Anhui Authent Chinese Med Qu, Hefei, Peoples R China.
